Phenotypes associated with this allele

• Allele Symbol: Lepr^db-2J
• Allele Name: diabetes 2 Jackson
• Allele ID: MGI:1856010
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Lepr^db-2J/Lepr^db-2J	involves: C57BL/6J * STOCK Tyrp1^b Whrn^wi	MGI:3813259

Genotype
MGI:3813259

hm1

• Allelic Composition: Lepr^db-2J/Lepr^db-2J
• Genetic Background: involves: C57BL/6J * STOCK Tyrp1^b Whrn^wi

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

small male preputial gland ( J:6157 )

♂ • the weight of the preputial gland is half of wild-typethe weight of the preputial gland is half of wild-type

small uterus ( J:6157 )

♀

constricted vagina orifice ( J:6157 )

♀

abnormal diestrus ( J:6157 )

♀ • mice exhibit diestrous vaginal acyclicity or occasional metestrous acyclicity

abnormal metestrus ( J:6157 )

♀ • mice exhibit diestrous vaginal acyclicity or occasional metestrous acyclicity

female infertility ( J:6157 )

♀

behavior/neurological

reduced male mating frequency ( J:6157 )

♂

homeostasis/metabolism

abnormal hormone level ( J:6157 )

• female mice exhibit an increase in hypothalamic gonadotrophin releasing hormone compared to in wild-type mice

decreased follicle stimulating hormone level ( J:6157 )

• in female mice

endocrine/exocrine glands

small male preputial gland ( J:6157 )

♂ • the weight of the preputial gland is half of wild-typethe weight of the preputial gland is half of wild-type

renal/urinary system

small male preputial gland ( J:6157 )

♂ • the weight of the preputial gland is half of wild-typethe weight of the preputial gland is half of wild-type

integument

small male preputial gland ( J:6157 )

♂ • the weight of the preputial gland is half of wild-typethe weight of the preputial gland is half of wild-type