All Phenotypes Edar<Dl-slk> MGI Mouse

Phenotypes associated with this allele

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Edar^Dl-slk/Edar^Dl-slk	Not Specified	MGI:5013400
ht2	Edar^Dl-slk/Edar⁺	Not Specified	MGI:4868752

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal tooth morphology ( J:6308 )

• dental abnormalities are the same as known to occur in mice homozygous or hemizygous for Eda^Ta

abnormal incisor morphology ( J:6308 )

• incisors are small or absent

absent incisors ( J:6308 )

small incisors ( J:6308 )

abnormal molar cusp morphology ( J:5886 )

• cusp B1 of m¹ is absent

• cusp B3 of m¹ and m² are usually absent

• a ridge of variable height connects cusps B1 and L1, running transversely across the anterior end of the crown of m²

abnormal molar root morphology ( J:5886 )

• the root of m¹ is usually single, though sometimes two or three roots are present

decreased molar number ( J:6308 )

absent molars ( J:6308 )

• upper and lower third molars are small or absent

small molars ( J:6308 )

• upper and lower third molars are small or absent

• first and second molars are smaller than normal

craniofacial

abnormal tooth morphology ( J:6308 )

• dental abnormalities are the same as known to occur in mice homozygous or hemizygous for Eda^Ta

abnormal incisor morphology ( J:6308 )

• incisors are small or absent

absent incisors ( J:6308 )

small incisors ( J:6308 )

abnormal molar cusp morphology ( J:5886 )

• cusp B1 of m¹ is absent

• cusp B3 of m¹ and m² are usually absent

• a ridge of variable height connects cusps B1 and L1, running transversely across the anterior end of the crown of m²

abnormal molar root morphology ( J:5886 )

• the root of m¹ is usually single, though sometimes two or three roots are present

decreased molar number ( J:6308 )

absent molars ( J:6308 )

• upper and lower third molars are small or absent

small molars ( J:6308 )

• upper and lower third molars are small or absent

• first and second molars are smaller than normal

integument

abnormal coat appearance ( J:6308 )

• mice look like homozygous or heterozygous Edar^dl mice

• coat is shiny and thin with bald patches behind the ears but the tail is sparsely haired rather than bald

abnormal vibrissa number ( J:6308 )

• reduced number of vibrissae but more than found in the homozygous mouse

growth/size/body

abnormal tooth morphology ( J:6308 )

• dental abnormalities are the same as known to occur in mice homozygous or hemizygous for Eda^Ta

abnormal incisor morphology ( J:6308 )

• incisors are small or absent

absent incisors ( J:6308 )

small incisors ( J:6308 )

abnormal molar cusp morphology ( J:5886 )

• cusp B1 of m¹ is absent

• cusp B3 of m¹ and m² are usually absent

• a ridge of variable height connects cusps B1 and L1, running transversely across the anterior end of the crown of m²

abnormal molar root morphology ( J:5886 )

• the root of m¹ is usually single, though sometimes two or three roots are present

decreased molar number ( J:6308 )

absent molars ( J:6308 )

• upper and lower third molars are small or absent

small molars ( J:6308 )

• upper and lower third molars are small or absent

• first and second molars are smaller than normal

Allelic Composition	Edar^Dl-slk/Edar⁺
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Edar^Dl-slk mutation (0 available); any Edar mutation (30 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal tooth morphology ( J:5886 )

• dental abnormalities are the same as known to occur in mice homozygous or hemizygous for Eda^Ta

abnormal incisor morphology ( J:5886 )

• incisors are small or absent

absent incisors ( J:5886 )

small incisors ( J:5886 )

abnormal molar cusp morphology ( J:5886 )

• cusp B1 of m¹ is absent

• cusp B3 of m¹ and m² are usually absent

• a ridge of variable height connects cusps B1 and L1, running transversely across the anterior end of the crown of m²

abnormal molar root morphology ( J:5886 )

• the root of m¹ is usually single, though sometimes two or three roots are present

decreased molar number ( J:5886 )

absent molars ( J:5886 )

• upper and lower third molars are small or absent

small molars ( J:5886 )

• upper and lower third molars are small or absent

• first and second molars are smaller than normal

craniofacial

abnormal tooth morphology ( J:5886 )

• dental abnormalities are the same as known to occur in mice homozygous or hemizygous for Eda^Ta

abnormal incisor morphology ( J:5886 )

• incisors are small or absent

absent incisors ( J:5886 )

small incisors ( J:5886 )

abnormal molar cusp morphology ( J:5886 )

• cusp B1 of m¹ is absent

• cusp B3 of m¹ and m² are usually absent

• a ridge of variable height connects cusps B1 and L1, running transversely across the anterior end of the crown of m²

abnormal molar root morphology ( J:5886 )

• the root of m¹ is usually single, though sometimes two or three roots are present

decreased molar number ( J:5886 )

absent molars ( J:5886 )

• upper and lower third molars are small or absent

small molars ( J:5886 )

• upper and lower third molars are small or absent

• first and second molars are smaller than normal

integument

abnormal coat appearance ( J:6308 )

• mice look like homozygous or heterozygous Edar^dl mice

• coat is shiny and thin with bald patches behind the ears but the tail is sparsely haired rather than bald

abnormal vibrissa number ( J:6308 )

• reduced number of vibrissae but more than found in the homozygous mouse

growth/size/body

abnormal tooth morphology ( J:5886 )

• dental abnormalities are the same as known to occur in mice homozygous or hemizygous for Eda^Ta

abnormal incisor morphology ( J:5886 )

• incisors are small or absent

absent incisors ( J:5886 )

small incisors ( J:5886 )

abnormal molar cusp morphology ( J:5886 )

• cusp B1 of m¹ is absent

• cusp B3 of m¹ and m² are usually absent

• a ridge of variable height connects cusps B1 and L1, running transversely across the anterior end of the crown of m²

abnormal molar root morphology ( J:5886 )

• the root of m¹ is usually single, though sometimes two or three roots are present

decreased molar number ( J:5886 )

absent molars ( J:5886 )

• upper and lower third molars are small or absent

small molars ( J:5886 )

• upper and lower third molars are small or absent

• first and second molars are smaller than normal

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24