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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mc1rE-tob
tobacco darkening
MGI:1856030
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		A/A
Mc1rE-tob/Mc1rE-tob 		M. m. domesticus poschiavinus MGI:3687979
cx2
 		A/A
Mc1rE-tob/Mc1r+ 		M. m. domesticus poschiavinus MGI:5629972


Genotype
MGI:3687979
cx1
Allelic
Composition		 A/A
Mc1rE-tob/Mc1rE-tob
Genetic
Background		 M. m. domesticus poschiavinus
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (19 available); any a mutation (463 available)
Mc1rE-tob mutation (4 available); any Mc1r mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
abnormal coat/hair pigmentation ( J:22593 )
• Mc1rE-tob influences the expression of agouti
darkened coat color ( J:22593 )
• the color is difficult to distinguish from non-agouti black before 8 weeks of age when agouti hairs appear on the flanks; the back remains darkened
• Mc1rE-tob/Mc1re mice that are also homozygous non-agouti are black because Mc1rE-tob only affects the expression of agouti

integument
abnormal coat/hair pigmentation ( J:22593 )
• Mc1rE-tob influences the expression of agouti
darkened coat color ( J:22593 )
• the color is difficult to distinguish from non-agouti black before 8 weeks of age when agouti hairs appear on the flanks; the back remains darkened
• Mc1rE-tob/Mc1re mice that are also homozygous non-agouti are black because Mc1rE-tob only affects the expression of agouti




Genotype
MGI:5629972
cx2
Allelic
Composition		 A/A
Mc1rE-tob/Mc1r+
Genetic
Background		 M. m. domesticus poschiavinus
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A mutation (19 available); any a mutation (463 available)
Mc1rE-tob mutation (4 available); any Mc1r mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
abnormal coat/hair pigmentation ( J:22593 )
• Mc1rE-tob influences the expression of agouti
darkened coat color ( J:22593 )
• the color is difficult to distinguish from non-agouti black before 8 weeks of age when some agouti hairs appear on the flanks; the back remains darkened
• Mc1rE-tob/Mc1re A/a mice have a darkened back

pigmentation
abnormal coat/hair pigmentation ( J:22593 )
• Mc1rE-tob influences the expression of agouti
darkened coat color ( J:22593 )
• the color is difficult to distinguish from non-agouti black before 8 weeks of age when some agouti hairs appear on the flanks; the back remains darkened
• Mc1rE-tob/Mc1re A/a mice have a darkened back




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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory