Phenotypes associated with this allele

• Allele Symbol: Grid2^ho-cpr
• Allele Name: creeper
• Allele ID: MGI:1856049
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grid2^ho-cpr/Grid2^ho-cpr	involves: C57BL/10J * DBA/2J	MGI:3844244

Genotype
MGI:3844244

hm1

• Allelic Composition: Grid2^ho-cpr/Grid2^ho-cpr
• Genetic Background: involves: C57BL/10J * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased survivor rate ( J:13994 )

• Background Sensitivity: mice that survive have a normal life span

postnatal lethality ( J:13994 )

• Background Sensitivity: the number of mutants that die can range from 12% to 47% depending on genetic background

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:13994 )

• Background Sensitivity: mutants can be identified between 14 and 25 days of age on this background but abnormal phenotype may not be seen for 50 days depending on genetic background

athetotic walking movements ( J:13994 )

• mice prop themselves with their chins during attempted walking movements

• severity is constant with advancing age

ataxia ( J:13994 )

abnormal resting posture ( J:13994 )

• mice rest on their bellies

nervous system

abnormal myelination ( J:13994 )

• suggested by luxol fast blue staining of histological sections

reproductive system

male infertility ( J:13994 )

♂ • Background Sensitivity: males on the original strain are infertile but can be fertile on hybrid backgrounds