Analysis Tools
mortality/aging
 |
• some survive post weaning but most die before 2 weeks of age
|
|
|
• partial pre-natal lethality
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reproductive system
|
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• litter size is about 25% smaller than in controls
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pigmentation
|
|
(J:249)
• irregular patches of full colored and very lightly colored fur over the whole coat
(J:13041)
• most female heterozygotes have mottled coats, due to the Lyon effect, inactivation of one or the other of the X chromosomes; the mutant gene is active in the light patches, the wild-type gene in the dark
(J:13041)
|
integument
|
|
(J:249)
• irregular patches of full colored and very lightly colored fur over the whole coat
(J:13041)
• most female heterozygotes have mottled coats, due to the Lyon effect, inactivation of one or the other of the X chromosomes; the mutant gene is active in the light patches, the wild-type gene in the dark
(J:13041)
|
curly vibrissae
(
J:249
)
|
|
• curling of vibrissae although the hairs of the coat are not noticeably waved
|
Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| Menkes disease | DOID:1838 |
OMIM:309400 |
J:249 | |
