All Phenotypes Oca2<p> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Oca2^p
pink-eyed dilution
MGI:1856114

Summary

29 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Oca2^p/Oca2^p	Not Specified	MGI:3844121
ht2	Oca2^p-61H/Oca2^p	involves: 101/H	MGI:5301962
ht3	Oca2^p-96H/Oca2^p	involves: 101/H	MGI:5301993
ht4	Oca2^p-88H/Oca2^p	involves: 101/H	MGI:5428850
ht5	Oca2^p-93H/Oca2^p	involves: 101/H	MGI:5301989
ht6	Oca2^p-92H/Oca2^p	involves: 101/H	MGI:5301987
ht7	Oca2^p-66H/Oca2^p	involves: 101/H	MGI:5301966
ht8	Oca2^p-95H/Oca2^p	involves: 101/H * C3H/HeH	MGI:5301991
ht9	Oca2^p-98H/Oca2^p	involves: 101/H * C3H/HeH	MGI:5301997
ht10	Oca2^p-86H/Oca2^p	involves: 101/H * C3H/HeH	MGI:5428845
ht11	Oca2^p-87H/Oca2^p	involves: 101/H * C3H/HeH	MGI:5428848
ht12	Oca2^p-55H/Oca2^p	involves: 101/H * C3H/HeH	MGI:5301960
ht13	Oca2^p-91H/Oca2^p	involves: 101/H * C3H/HeH	MGI:5301986
ht14	Oca2^p/Oca2^p-80K	involves: 101/Rl * C3H/Rl	MGI:3849875
ht15	Oca2^p/Oca2^p-7R	involves: 101/Rl * C3H/Rl	MGI:3612259
ht16	Oca2^p/Oca2^p-8FDFoD	involves: 101/Rl * C3H/Rl	MGI:3849885
ht17	Oca2^p/Oca2^p-116G	involves: 101/Rl * C3H/Rl	MGI:3849992
ht18	Oca2^p/Oca2^p-103G	involves: 101/Rl * C3H/Rl	MGI:3612261
ht19	Oca2^p-85H/Oca2^p	involves: C3H/HeH	MGI:5301984
ht20	Oca2^p-65H/Oca2^p	involves: C3H/HeH	MGI:5301964
ht21	Oca2^p-78H/Oca2^p	involves: C3H/HeH	MGI:5301969
ht22	Oca2^p-80H/Oca2^p	involves: C3H/HeH	MGI:5301980
ht23	Oca2^p-83H/Oca2^p	involves: C3H/HeH	MGI:5301982
ht24	Oca2^p-12DTR/Oca2^p	Not Specified	MGI:3826442
cx25	a/a Myo5a^d/Myo5a⁺ Oca2^p/Oca2⁺ Tyrp1^B-lt/Tyrp1⁺	involves: C58 * CT/Ch	MGI:3795191
cx26	Lyst^bg-slt/Lyst^bg-slt Oca2^p/Oca2^p	involves: CT/Ch * YZ57/Ch	MGI:2661158
cx27	Lyst^bg-slt/Lyst^bg-slt Myo5a^d/Myo5a^d Oca2^p/Oca2^p Tyrp1^b/Tyrp1^b	involves: CT/Ch * YZ57/Ch	MGI:2661267
cx28	Oca2^p/Oca2^p Tyr^c-i/Tyr^c-i	involves: STOCK Tyr^c-r	MGI:2663251
cx29	a/a Oca2^p/Oca2^p	Not Specified	MGI:3844692

Allelic Composition	Oca2^p/Oca2^p
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

decreased eye pigmentation ( J:2108 )

vision/eye

decreased eye pigmentation ( J:2108 )

Allelic Composition	Oca2^p-61H/Oca2^p
Genetic Background	involves: 101/H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-61H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:179354 )

• coat is slightly darker than in Oca2^p homozygotes

pigmentation

abnormal coat/hair pigmentation ( J:179354 )

• coat is slightly darker than in Oca2^p homozygotes

Allelic Composition	Oca2^p-96H/Oca2^p
Genetic Background	involves: 101/H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-96H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

cleft palate ( J:179354 )

digestive/alimentary system

cleft palate ( J:179354 )

growth/size/body

cleft palate ( J:179354 )

Allelic Composition	Oca2^p-88H/Oca2^p
Genetic Background	involves: 101/H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-88H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:2108 , J:78801 )

• similar to homozygous Oca2^p mice (J:2108)

• on this background reduced pigmentation in the coat results in a yellow coat color (J:78801)

pigmentation

abnormal coat/hair pigmentation ( J:2108 , J:78801 )

• similar to homozygous Oca2^p mice (J:2108)

• on this background reduced pigmentation in the coat results in a yellow coat color (J:78801)

decreased eye pigmentation ( J:78801 )

• eye color has a pink tint, similar to the eyes of albino mice

vision/eye

decreased eye pigmentation ( J:78801 )

• eye color has a pink tint, similar to the eyes of albino mice

Allelic Composition	Oca2^p-93H/Oca2^p
Genetic Background	involves: 101/H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-93H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

pigmentation

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

Allelic Composition	Oca2^p-92H/Oca2^p
Genetic Background	involves: 101/H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-92H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:179354 )

• mice are viable

Allelic Composition	Oca2^p-66H/Oca2^p
Genetic Background	involves: 101/H

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-66H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:179354 )

• ruby eyes, light colored ears and tail, sandy brown tips to fur, dark under fur

decreased tail pigmentation ( J:179354 )

pigmentation

abnormal coat/hair pigmentation ( J:179354 )

• ruby eyes, light colored ears and tail, sandy brown tips to fur, dark under fur

decreased tail pigmentation ( J:179354 )

abnormal eye pigmentation ( J:179354 )

• ruby eyes

limbs/digits/tail

decreased tail pigmentation ( J:179354 )

vision/eye

abnormal eye pigmentation ( J:179354 )

• ruby eyes

Allelic Composition	Oca2^p-95H/Oca2^p
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-95H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

pigmentation

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

Allelic Composition	Oca2^p-98H/Oca2^p
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-98H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

pigmentation

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

Allelic Composition	Oca2^p-86H/Oca2^p
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-86H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:2108 , J:78801 )

• color is similar to homozygous Oca2^p mice (J:2108)

• on this background reduced pigmentation in the coat results in a yellow coat color (J:78801)

pigmentation

abnormal coat/hair pigmentation ( J:2108 , J:78801 )

• color is similar to homozygous Oca2^p mice (J:2108)

• on this background reduced pigmentation in the coat results in a yellow coat color (J:78801)

decreased eye pigmentation ( J:78801 )

• eyes have a pink tint, resembling eyes of albino mice

vision/eye

decreased eye pigmentation ( J:78801 )

• eyes have a pink tint, resembling eyes of albino mice

Allelic Composition	Oca2^p-87H/Oca2^p
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-87H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:2108 , J:78801 )

• color is similar to homozygous Oca2^p mice (J:2108)

• on this background reduced pigmentation in the coat results in a yellow coat color (J:78801)

pigmentation

abnormal coat/hair pigmentation ( J:2108 , J:78801 )

• color is similar to homozygous Oca2^p mice (J:2108)

• on this background reduced pigmentation in the coat results in a yellow coat color (J:78801)

decreased eye pigmentation ( J:78801 )

• eye color has a pink tint, similar to the eyes of albino mice

vision/eye

decreased eye pigmentation ( J:78801 )

• eye color has a pink tint, similar to the eyes of albino mice

Allelic Composition	Oca2^p-55H/Oca2^p
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-55H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

pigmentation

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

Allelic Composition	Oca2^p-91H/Oca2^p
Genetic Background	involves: 101/H * C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-91H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

pigmentation

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

Allelic Composition	Oca2^p/Oca2^p-80K
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-80K mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:100221 )

• reduced eumelanin pigmentation in hair

absent eye pigmentation ( J:100221 )

vision/eye

absent eye pigmentation ( J:100221 )

integument

abnormal coat/hair pigmentation ( J:100221 )

• reduced eumelanin pigmentation in hair

Allelic Composition	Oca2^p/Oca2^p-7R
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-7R mutation (27 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

darkened coat color ( J:100221 )

• reduced eumelanin in the hair

• pigmentation intermediate between Oca2^p/Oca2^p and wild-type

abnormal eye pigmentation ( J:100221 )

• eye pigment reduced

vision/eye

abnormal eye pigmentation ( J:100221 )

• eye pigment reduced

integument

darkened coat color ( J:100221 )

• reduced eumelanin in the hair

• pigmentation intermediate between Oca2^p/Oca2^p and wild-type

Allelic Composition	Oca2^p/Oca2^p-8FDFoD
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-8FDFoD mutation (1 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:100221 )

• reduced eumelanin pigmentation in hair

absent eye pigmentation ( J:100221 )

vision/eye

absent eye pigmentation ( J:100221 )

integument

abnormal coat/hair pigmentation ( J:100221 )

• reduced eumelanin pigmentation in hair

Allelic Composition	Oca2^p/Oca2^p-116G
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-116G mutation (1 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:100221 )

• reduced eumelanin pigmentation in hair

absent eye pigmentation ( J:100221 )

vision/eye

absent eye pigmentation ( J:100221 )

integument

abnormal coat/hair pigmentation ( J:100221 )

• reduced eumelanin pigmentation in hair

Allelic Composition	Oca2^p/Oca2^p-103G
Genetic Background	involves: 101/Rl * C3H/Rl

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-103G mutation (1 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

darkened coat color ( J:100221 )

• reduced eumelanin pigmentation in hair

• fur darker than Oca2^p/Oca2^p

abnormal eye pigmentation ( J:100221 )

• eye pigment reduced, but eyes virtually fully pigmented from birth on

vision/eye

abnormal eye pigmentation ( J:100221 )

• eye pigment reduced, but eyes virtually fully pigmented from birth on

integument

darkened coat color ( J:100221 )

• reduced eumelanin pigmentation in hair

• fur darker than Oca2^p/Oca2^p

Allelic Composition	Oca2^p-85H/Oca2^p
Genetic Background	involves: C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-85H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

pigmentation

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

Allelic Composition	Oca2^p-65H/Oca2^p
Genetic Background	involves: C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-65H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal eye pigmentation ( J:179354 )

• eye color is darker tha in Oca2^p homozygotes

vision/eye

abnormal eye pigmentation ( J:179354 )

• eye color is darker tha in Oca2^p homozygotes

Allelic Composition	Oca2^p-78H/Oca2^p
Genetic Background	involves: C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-78H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

diluted coat color ( J:179354 )

pigmentation

diluted coat color ( J:179354 )

Allelic Composition	Oca2^p-80H/Oca2^p
Genetic Background	involves: C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-80H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

pigmentation

abnormal coat/hair pigmentation ( J:179354 )

• mice resemble Oca2^p homozygotes

Allelic Composition	Oca2^p-83H/Oca2^p
Genetic Background	involves: C3H/HeH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-83H mutation (0 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

integument

abnormal coat/hair pigmentation ( J:179354 )

• coat is slightly darker than in Oca2^p homozygotes

pigmentation

abnormal coat/hair pigmentation ( J:179354 )

• coat is slightly darker than in Oca2^p homozygotes

Allelic Composition	Oca2^p-12DTR/Oca2^p
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Oca2^p-12DTR mutation (1 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:29903 )

• coat color (eumelanin pigment) is intermediate between the coat color of Oca2^p/Oca2^p and wild-type mice

decreased eye pigmentation ( J:29903 )

• eyes of newborns are not fully pigmented and darken with age

vision/eye

decreased eye pigmentation ( J:29903 )

• eyes of newborns are not fully pigmented and darken with age

integument

diluted coat color ( J:29903 )

• coat color (eumelanin pigment) is intermediate between the coat color of Oca2^p/Oca2^p and wild-type mice

Allelic Composition	a/a Myo5a^d/Myo5a⁺ Oca2^p/Oca2⁺ Tyrp1^B-lt/Tyrp1⁺
Genetic Background	involves: C58 * CT/Ch

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (229 available); any a mutation (463 available)
Myo5a^d mutation (105 available); any Myo5a mutation (265 available)
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Tyrp1^B-lt mutation (4 available); any Tyrp1 mutation (162 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:13094 )

• dark sepia in color

• unlike mice wildtype for pink-eye the hairs are pigmented from tip to base and do not have large clumps of pigment, but may have small clumps of pigment

integument

diluted coat color ( J:13094 )

• dark sepia in color

• unlike mice wildtype for pink-eye the hairs are pigmented from tip to base and do not have large clumps of pigment, but may have small clumps of pigment

Allelic Composition	Lyst^bg-slt/Lyst^bg-slt Oca2^p/Oca2^p
Genetic Background	involves: CT/Ch * YZ57/Ch

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyst^bg-slt mutation (0 available); any Lyst mutation (225 available)
Oca2^p mutation (11 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:25388 )

• coat was slightly lighter than those of mice homozygous for p alone

• cortical pigment was absent

• the few medullary septae that lacked pigment were in the distal hair shaf

• granules resembled those of mice homozygous for p alone except a few were larger

abnormal eye pigmentation ( J:25388 )

• eye color was pink

vision/eye

abnormal eye pigmentation ( J:25388 )

• eye color was pink

integument

diluted coat color ( J:25388 )

• coat was slightly lighter than those of mice homozygous for p alone

• cortical pigment was absent

• the few medullary septae that lacked pigment were in the distal hair shaf

• granules resembled those of mice homozygous for p alone except a few were larger

Allelic Composition	Lyst^bg-slt/Lyst^bg-slt Myo5a^d/Myo5a^d Oca2^p/Oca2^p Tyrp1^b/Tyrp1^b
Genetic Background	involves: CT/Ch * YZ57/Ch

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lyst^bg-slt mutation (0 available); any Lyst mutation (225 available)
Myo5a^d mutation (105 available); any Myo5a mutation (265 available)
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Tyrp1^b mutation (29 available); any Tyrp1 mutation (162 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

diluted coat color ( J:83269 )

integument

diluted coat color ( J:83269 )

premature hair loss ( J:83269 )

• random thinning of the coat appeared during the third week of age

abnormal hair cycle ( J:83269 )

delayed hair regrowth ( J:83269 )

• coat thinning at three weeks of age was followed by a short lag in the second hair growth cycle

Allelic Composition	Oca2^p/Oca2^p Tyr^c-i/Tyr^c-i
Genetic Background	involves: STOCK Tyr^c-r

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oca2^p mutation (11 available); any Oca2 mutation (70 available)
Tyr^c-i mutation (0 available); any Tyr mutation (379 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

abnormal coat/hair pigmentation ( J:83666 )

• buff colored coat

integument

abnormal coat/hair pigmentation ( J:83666 )

• buff colored coat

Allelic Composition	a/a Oca2^p/Oca2^p
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
a mutation (229 available); any a mutation (463 available)
Oca2^p mutation (11 available); any Oca2 mutation (70 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

decreased tail pigmentation ( J:78801 )

• the tail has much less pigment than normal mice

pigmentation

decreased ear pigmentation ( J:36414 , J:78801 )

• the ears appear much lighter than ears of normal mice (J:78801)

abnormal coat/hair pigmentation ( J:12958 , J:78801 )

abnormal hair follicle melanocyte morphology ( J:78801 )

• black and brown pigmentation in hair is significantly reduced

abnormal hair follicle melanin granule morphology ( J:12958 )

• pigment granules are not diluted but no longer evenly distributed, found as flecks and large loose clumps

• the color quality of the pigment is not altered but there are fewer cortical granules and an increase in pigmentation lag

abnormal hair follicle melanin granule distribution ( J:12958 )

• pigment occurs in loose clumps

abnormal hair follicle melanin granule shape ( J:12958 )

decreased tail pigmentation ( J:78801 )

• the tail has much less pigment than normal mice

decreased skin pigmentation ( J:36414 )

decreased eye pigmentation ( J:78801 )

• eyes are similar in color to eyes of albino mice

vision/eye

decreased eye pigmentation ( J:78801 )

• eyes are similar in color to eyes of albino mice

craniofacial

decreased ear pigmentation ( J:36414 , J:78801 )

• the ears appear much lighter than ears of normal mice (J:78801)

hearing/vestibular/ear

decreased ear pigmentation ( J:36414 , J:78801 )

• the ears appear much lighter than ears of normal mice (J:78801)

integument

decreased ear pigmentation ( J:36414 , J:78801 )

• the ears appear much lighter than ears of normal mice (J:78801)

abnormal coat/hair pigmentation ( J:12958 , J:78801 )

abnormal hair follicle melanocyte morphology ( J:78801 )

• black and brown pigmentation in hair is significantly reduced

abnormal hair follicle melanin granule morphology ( J:12958 )

• pigment granules are not diluted but no longer evenly distributed, found as flecks and large loose clumps

• the color quality of the pigment is not altered but there are fewer cortical granules and an increase in pigmentation lag

abnormal hair follicle melanin granule distribution ( J:12958 )

• pigment occurs in loose clumps

abnormal hair follicle melanin granule shape ( J:12958 )

decreased tail pigmentation ( J:78801 )

• the tail has much less pigment than normal mice

decreased skin pigmentation ( J:36414 )

growth/size/body

decreased ear pigmentation ( J:36414 , J:78801 )

• the ears appear much lighter than ears of normal mice (J:78801)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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