Phenotypes associated with this allele

• Allele Symbol: Krt25^Re
• Allele Name: rex
• Allele ID: MGI:1856137
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Krt25^Re/Krt25^Re	B6.Cg-Pmp22^Tr-J Krt25^Re/+ +/J	MGI:3771969
hm2	Krt25^Re/Krt25^Re	Not Specified	MGI:2672141
ht3	Krt25^Re/Krt25^+	Not Specified	MGI:2672142

Genotype
MGI:3771969

hm1

• Allelic Composition: Krt25^Re/Krt25^Re
• Genetic Background: B6.Cg-Pmp22^Tr-J Krt25^Re/+ +/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:130100 )

endocrine/exocrine glands

enlarged sebaceous gland ( J:130100 )

integument

enlarged sebaceous gland ( J:130100 )

waved hair ( J:130100 )

• beginning at 1 month of age pelage is wavy compared to wild-type mice but this waviness becomes weaker as mice age

abnormal hair shaft morphology ( J:130100 )

• at 1 month, hair shafts are fragile

abnormal hair follicle morphology ( J:130100 )

• at 1 month, hair follicles are bent and shorter than in wild-type mice

curly vibrissae ( J:130100 )

• beginning at 1 month of age, whiskers are irregular and fragile

Genotype
MGI:2672141

hm2

• Allelic Composition: Krt25^Re/Krt25^Re
• Genetic Background: Not Specified

integument

abnormal hair texture ( J:15328 )

rough coat ( J:15328 )

• mice have roughish coats

waved hair ( J:15328 )

• mice exhibit wavy coats when young but not during adulthood

abnormal hair shaft morphology ( J:15247 )

• the hair shaft is irregular

increased curvature of guard hairs ( J:15328 )

• mice exhibit short, curly and irregular guard hairs

abnormal hair follicle inner root sheath morphology ( J:15247 )

• the layers of the inner root sheath are irregular

curly vibrissae ( J:15328 )

• vibrassae are curly

Genotype
MGI:2672142

ht3

• Allelic Composition: Krt25^Re/Krt25⁺
• Genetic Background: Not Specified

integument

abnormal hair texture ( J:15328 )

rough coat ( J:15328 )

• mice have roughish coats

waved hair ( J:15328 )

• mice exhibit wavy coats when young but not during adulthood

abnormal hair shaft morphology ( J:15247 )

• the hair shaft is irregular

increased curvature of guard hairs ( J:15328 )

• mice exhibit short, curly and irregular guard hairs

curly vibrissae ( J:15328 )

• vibrassae are curly