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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		KitlSl-m
mutant from steel
MGI:1856166
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		KitlSl-m/KitlSl-m involves: C57BL/6 MGI:5142491
ht2
 		KitlSl-m/Kitl+ involves: C57BL/6 MGI:5142489


Genotype
MGI:5142491
hm1
Allelic
Composition		 KitlSl-m/KitlSl-m
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-m mutation (0 available); any Kitl mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
anemia ( J:5009 , J:13416 )
• due to loss of blood through their gastrointestinal tracts (J:13416)
• blood sampled from the tail vein has a greatly decreased RBC count and greatly increased MCV (J:13416)

integument
abnormal coat/hair pigmentation ( J:13416 )
• slightly anemic
absent coat pigmentation ( J:13416 )
• mice are strikingly white with (normal) black eyes

pigmentation
abnormal coat/hair pigmentation ( J:13416 )
• slightly anemic
absent coat pigmentation ( J:13416 )
• mice are strikingly white with (normal) black eyes

reproductive system
reduced female fertility ( J:13137 , J:13416 )
• notall females are fertile and no fertile female has had more than one litter (J:13137)
(J:13416)

cardiovascular system
gastrointestinal hemorrhage ( J:5009 )
• mice lose approximately 3.5 per cent of their blood volume into their gastrointestinal tract daily
• study shows iron is lost but red blood cell loss was not demonstrated

digestive/alimentary system
gastrointestinal hemorrhage ( J:5009 )
• mice lose approximately 3.5 per cent of their blood volume into their gastrointestinal tract daily
• study shows iron is lost but red blood cell loss was not demonstrated

mortality/aging
premature death ( J:5009 , J:13416 )
• occasionally a mouse has survived up to a year (J:13416)




Genotype
MGI:5142489
ht2
Allelic
Composition		 KitlSl-m/Kitl+
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-m mutation (0 available); any Kitl mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument

pigmentation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory