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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		KitlSl-J
steel Jackson
MGI:1856170
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		KitlSl-J/KitlSl-J C3HeB/FeHu-KitlSl-J MGI:3833574
ht2
 		KitlSl-J/Kitl+ C3HeB/FeHu-KitlSl-J MGI:3833576
ht3
 		KitlSl-J/Kitl+ involves: 129 MGI:3833649


Genotype
MGI:3833574
hm1
Allelic
Composition		 KitlSl-J/KitlSl-J
Genetic
Background		 C3HeB/FeHu-KitlSl-J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-J mutation (1 available); any Kitl mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
perinatal lethality, complete penetrance ( J:145144 )
• mice die from severe anemia

hematopoietic system

endocrine/exocrine glands
abnormal seminiferous tubule morphology ( J:145144 )
• contain only Sertoli cells

reproductive system
absent germ cells ( J:145144 )
• in both females and males
abnormal seminiferous tubule morphology ( J:145144 )
• contain only Sertoli cells

cellular
absent germ cells ( J:145144 )
• in both females and males




Genotype
MGI:3833576
ht2
Allelic
Composition		 KitlSl-J/Kitl+
Genetic
Background		 C3HeB/FeHu-KitlSl-J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-J mutation (1 available); any Kitl mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:145144 )
• lightened coat color compared to normal and the belly is very light
white spotting ( J:145144 )
• the feet and tail tip are white
• a white dot on the head is characteristic
belly spot ( J:145144 )
• a mid-ventral white streak becomes more apparent with age

integument
diluted coat color ( J:145144 )
• lightened coat color compared to normal and the belly is very light
white spotting ( J:145144 )
• the feet and tail tip are white
• a white dot on the head is characteristic
belly spot ( J:145144 )
• a mid-ventral white streak becomes more apparent with age




Genotype
MGI:3833649
ht3
Allelic
Composition		 KitlSl-J/Kitl+
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitlSl-J mutation (1 available); any Kitl mutation (94 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased testicular teratoma incidence ( J:50508 )
• Background Sensitivity: tumor incidence is markedly increased in the presence of this allele
• Background Sensitivity: in the presence of this allele, appreciable differences are seen in the incidence of tumors among 129 sublines

endocrine/exocrine glands
increased testicular teratoma incidence ( J:50508 )
• Background Sensitivity: tumor incidence is markedly increased in the presence of this allele
• Background Sensitivity: in the presence of this allele, appreciable differences are seen in the incidence of tumors among 129 sublines

reproductive system
increased testicular teratoma incidence ( J:50508 )
• Background Sensitivity: in the presence of this allele, appreciable differences are seen in the incidence of tumors among 129 sublines
• Background Sensitivity: tumor incidence is markedly increased in the presence of this allele




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory