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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
KitW-37J
dominant spotting 37 Jackson
MGI:1856241
Summary 5 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
KitW-37J/KitW-37J C57BL/6J-KitW-37J/J MGI:3813672
ht2
KitW-37J/Kit+ C57BL/6J-KitW-37J/J MGI:3813673
ht3
KitW-37J/Kit+ involves: C57BL/6 * C57BL/6J MGI:3813820
ht4
KitW-37J/KitW involves: C57BL/6 * C57BL/6J * WB MGI:3813819
ht5
KitW-37J/KitW-39J involves: C57BL/6J MGI:3813689


Genotype
MGI:3813672
hm1
Allelic
Composition
KitW-37J/KitW-37J
Genetic
Background
C57BL/6J-KitW-37J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-37J mutation (2 available); any Kit mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• mice die in mid-gestation or immediately after birth
• mice die in mid-gestation or immediately after birth




Genotype
MGI:3813673
ht2
Allelic
Composition
KitW-37J/Kit+
Genetic
Background
C57BL/6J-KitW-37J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-37J mutation (2 available); any Kit mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• borderline

pigmentation
• some mice exhibit mosaic coat patterns
• 85% of the coat is white with flecks of pigmented hair on the head, around the eyes, at the base of the ears and on the rump

integument
• some mice exhibit mosaic coat patterns
• 85% of the coat is white with flecks of pigmented hair on the head, around the eyes, at the base of the ears and on the rump




Genotype
MGI:3813820
ht3
Allelic
Composition
KitW-37J/Kit+
Genetic
Background
involves: C57BL/6 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-37J mutation (2 available); any Kit mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice exhibit slightly fewer mast cells in the skin than wild-type mice

hematopoietic system
• mice exhibit slightly fewer mast cells in the skin than wild-type mice

pigmentation
• slightly

integument
• slightly




Genotype
MGI:3813819
ht4
Allelic
Composition
KitW-37J/KitW
Genetic
Background
involves: C57BL/6 * C57BL/6J * WB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW mutation (10 available); any Kit mutation (182 available)
KitW-37J mutation (2 available); any Kit mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• mice exhibit no mast cells in the skin
• mast cells do not survive co-culture with fibroblast cells and exhibit impaired attachment

hematopoietic system
• mice exhibit no mast cells in the skin
• mast cells do not survive co-culture with fibroblast cells and exhibit impaired attachment

pigmentation
• mice are black-eyed with white coats

integument
• mice are black-eyed with white coats




Genotype
MGI:3813689
ht5
Allelic
Composition
KitW-37J/KitW-39J
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-37J mutation (2 available); any Kit mutation (182 available)
KitW-39J mutation (2 available); any Kit mutation (182 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• fewer than expected mice are born alive

reproductive system
• ovaries contain fewer developing follicles than in wild-type mice
• mice lack spermatogenic activity

endocrine/exocrine glands
• ovaries contain fewer developing follicles than in wild-type mice

pigmentation
• mice are black-eyed with white coats

integument
• mice are black-eyed with white coats





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory