All Phenotypes Kit<W-44J> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kit^W-44J
dominant spotting 44 Jackson
MGI:1856247

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kit^W-44J/Kit^W-44J	B6.C3-Kit^W-44J/J	MGI:3055514
ht2	Kit^W-44J/Kit⁺	B6.C3-Kit^W-44J/J	MGI:3055517
ht3	Kit^W-41J/Kit^W-44J	involves: C3H/HeJ * C57BL/6J	MGI:3813685
ht4	Kit^W-39J/Kit^W-44J	involves: C3H/HeJ * C57BL/6J	MGI:3813687

Allelic Composition	Kit^W-44J/Kit^W-44J
Genetic Background	B6.C3-Kit^W-44J/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-44J mutation (1 available); any Kit mutation (181 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal ovary morphology ( J:6571 )

• pathological invagination of the germinal epithelium by 2 months of age

abnormal ovarian follicle number ( J:6571 )

• ovaries contain fewer developing follicles than in wild-type mice

small ovary ( J:6571 )

reduced female fertility ( J:6571 )

• 50% are fertile and these produce one or two small litters

decreased litter size ( J:6571 )

• some female mice produce small litters

male infertility ( J:6571 )

• testes are less than a third normal size and devoid of spermatogenic activity

hematopoietic system

hematopoietic system phenotype ( J:6571 )

N	• no hematopoietic system abnormalities detected

pigmentation

irregular coat pigmentation ( J:6571 )

• mice exhibit a black-flecked white coat in which the dorsal coat has concentrated areas of black about the head and hind quarters and the ventral coat is white with black hair along lateral borders

endocrine/exocrine glands

abnormal ovary morphology ( J:6571 )

• pathological invagination of the germinal epithelium by 2 months of age

abnormal ovarian follicle number ( J:6571 )

• ovaries contain fewer developing follicles than in wild-type mice

small ovary ( J:6571 )

integument

irregular coat pigmentation ( J:6571 )

Allelic Composition	Kit^W-44J/Kit⁺
Genetic Background	B6.C3-Kit^W-44J/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-44J mutation (1 available); any Kit mutation (181 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

white spotting ( J:6571 )

• white feet and tail tip

belly spot ( J:6571 )

• very small spot to only a few hairs

hematopoietic system

hematopoietic system phenotype ( J:6571 )

N	• no hematopoietic system abnormalities detected

integument

white spotting ( J:6571 )

• white feet and tail tip

belly spot ( J:6571 )

• very small spot to only a few hairs

Allelic Composition	Kit^W-41J/Kit^W-44J
Genetic Background	involves: C3H/HeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-41J mutation (4 available); any Kit mutation (181 available)
Kit^W-44J mutation (1 available); any Kit mutation (181 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

reproductive system phenotype ( J:6571 )

N	• mice are fertile

abnormal ovarian follicle number ( J:6571 )

• ovaries contain fewer developing follicles than in wild-type mice

small ovary ( J:6571 )

endocrine/exocrine glands

abnormal ovarian follicle number ( J:6571 )

• ovaries contain fewer developing follicles than in wild-type mice

small ovary ( J:6571 )

Allelic Composition	Kit^W-39J/Kit^W-44J
Genetic Background	involves: C3H/HeJ * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-39J mutation (2 available); any Kit mutation (181 available)
Kit^W-44J mutation (1 available); any Kit mutation (181 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal ovarian follicle number ( J:6571 )

• ovaries contain fewer developing follicles than in wild-type mice

small ovary ( J:6571 )

small testis ( J:6571 )

• mice exhibit reduced testes size but maintain spermatogenesis

reduced female fertility ( J:6571 )

decreased litter size ( J:6571 )

• some female mice produce small litters

male infertility ( J:6571 )

endocrine/exocrine glands

abnormal ovarian follicle number ( J:6571 )

• ovaries contain fewer developing follicles than in wild-type mice

small ovary ( J:6571 )

small testis ( J:6571 )

• mice exhibit reduced testes size but maintain spermatogenesis

pigmentation

absent coat pigmentation ( J:6571 )

• mice are black-eyed with white coats and have fully pigmented ear pinnae

integument

absent coat pigmentation ( J:6571 )

• mice are black-eyed with white coats and have fully pigmented ear pinnae

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