All Phenotypes Grem1<ld-J> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Grem1^ld-J
limb deformity Jackson
MGI:1856290

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grem1^ld-J/Grem1^ld-J	involves: CBA/Ca	MGI:4355957
cx2	Alx4^lst/Alx4⁺ Grem1^ld-J/Grem1⁺	involves: CBA/Ca * NHO	MGI:4355958

Allelic Composition	Grem1^ld-J/Grem1^ld-J
Genetic Background	involves: CBA/Ca

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grem1^ld-J mutation (1 available); any Grem1 mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

renal/urinary system

absent kidney ( J:17401 )

• 19 of 49 lack both kidneys

single kidney ( J:17401 )

• 25 of 49 with one absent kidney

• 4 of 49 with only one hypomorphic kidney

abnormal ureteric bud elongation ( J:17401 )

• has not reached the metanephric mesenchyme by E11.5

Allelic Composition	Alx4^lst/Alx4⁺ Grem1^ld-J/Grem1⁺
Genetic Background	involves: CBA/Ca * NHO

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Alx4^lst mutation (0 available); any Alx4 mutation (21 available)
Grem1^ld-J mutation (1 available); any Grem1 mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

limbs/digits/tail phenotype ( J:35172 )

N	• have normal limbs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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