Phenotypes associated with this allele

• Allele Symbol: Fmn1^ld-TgHD
• Allele Name: limb deformity TgHD
• Allele ID: MGI:1856291
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fmn1^ld-TgHD/Fmn1^ld-TgHD	involves: BALB/c * C57BL/6 * CD-1 * FVB/N	MGI:4355954
hm2	Fmn1^ld-TgHD/Fmn1^ld-TgHD	involves: C57BL/6 * CD-1	MGI:4355953
cx3	Alx4^lst/Alx4^+ Fmn1^ld-TgHD/Fmn1^+	involves: BALB/c * C57BL/6 * CD-1 * FVB/N	MGI:4355955

Genotype
MGI:4355954

hm1

• Allelic Composition: Fmn1^ld-TgHD/Fmn1^ld-TgHD
• Genetic Background: involves: BALB/c * C57BL/6 * CD-1 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

abnormal kidney morphology ( J:17401 )

• 57% with some sort of kidney abnormality

absent kidney ( J:17401 )

• 5 of 44 lack both kidneys

single kidney ( J:17401 )

• 19 of 44 with one absent kidney

• 1 of 44 with only one, hypomorphic, kidney

Genotype
MGI:4355953

hm2

• Allelic Composition: Fmn1^ld-TgHD/Fmn1^ld-TgHD
• Genetic Background: involves: C57BL/6 * CD-1

limbs/digits/tail

fused carpal bones ( J:8077 )

• fusion of carpals

oligodactyly ( J:8077 )

• loss of postaxial digits on both fore- and hind-limbs

syndactyly ( J:8077 )

• fusion of digits in both the fore- and hind-limbs

fused phalanges ( J:8077 )

fused tarsal bones ( J:8077 )

abnormal forelimb morphology ( J:8077 )

• deformed

fused radius and ulna ( J:8077 )

• fusion of the radius with the ulna

abnormal hindlimb morphology ( J:8077 )

• deformed

abnormal fibula morphology ( J:8077 )

• fusion with tibia

abnormal tibia morphology ( J:8077 )

• fusion with fibula

fused metacarpal bones ( J:8077 )

• fusion of metacarpals

fused metatarsal bones ( J:8077 )

• fusion of metatarsals

skeleton

skeleton phenotype ( J:8077 )

N • axial skeleton is normal

fused carpal bones ( J:8077 )

• fusion of carpals

fused phalanges ( J:8077 )

fused tarsal bones ( J:8077 )

fused radius and ulna ( J:8077 )

• fusion of the radius with the ulna

abnormal fibula morphology ( J:8077 )

• fusion with tibia

abnormal tibia morphology ( J:8077 )

• fusion with fibula

fused metacarpal bones ( J:8077 )

• fusion of metacarpals

fused metatarsal bones ( J:8077 )

• fusion of metatarsals

Genotype
MGI:4355955

cx3

• Allelic Composition: Alx4^lst/Alx4⁺; Fmn1^ld-TgHD/Fmn1⁺
• Genetic Background: involves: BALB/c * C57BL/6 * CD-1 * FVB/N

limbs/digits/tail

limbs/digits/tail phenotype ( J:17401 )

N • have normal limbs