Phenotypes associated with this allele

• Allele Symbol: Reln^rl-Orl
• Allele Name: reeler Orleans
• Allele ID: MGI:1856416
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Reln^rl-Orl/Reln^rl-Orl	BALB/c-Reln^rl-Orl	MGI:3722254

Genotype
MGI:3722254

hm1

• Allelic Composition: Reln^rl-Orl/Reln^rl-Orl
• Genetic Background: BALB/c-Reln^rl-Orl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal olfactory bulb morphology ( J:121846 )

• olfactory bulbs contain only 60% of the number of cells in the granule cell layer compared to in wild-type mice

• ependymal zone of the bulb contains fewer cells

abnormal rostral migratory stream morphology ( J:121846 )

• at P17 and P61, rostral migratory streams of (RMS) neuroblasts are severely disrupted and neuroblasts accumulate in the subventricular zone

abnormal olfactory bulb granule cell layer morphology ( J:121846 )

• fewer cells that contribute to the olfactory bulb are found in the granule cell layer

abnormal postnatal subventricular zone morphology ( J:121846 )

• neuroblasts and glial cells accumulate in the subventricular zone

• a 15-fold increase in apoptosis in the subventricular zone is observed