Phenotypes associated with this allele

• Allele Symbol: Pcdh15^av
• Allele Name: Ames waltzer
• Allele ID: MGI:1856467
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Pcdh15^av/Pcdh15^av	involves: K	MGI:5642273

Genotype
MGI:5642273

hm1

• Allelic Composition: Pcdh15^av/Pcdh15^av
• Genetic Background: involves: K

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

abnormal organ of Corti morphology ( J:5225 )

• spaces normally containing fluid do not develop normally

• the organ of Corti is replaced by simple, cuboidal epithelium

abnormal cochlear hair cell morphology ( J:5225 )

• hair cells degenerate

absent tunnel of Corti ( J:5225 )

• spaces normally containing fluid are absent or late to develop

deafness ( J:5225 )

• there is no evidence of auditory function at any time point after birth

• auditory stimuli produced no behavioral or electrical responses from mutant mice

nervous system

abnormal cochlear hair cell morphology ( J:5225 )

• hair cells degenerate

abnormal cochlear ganglion morphology ( J:5225 )

• spiral ganglion cells degenerate

normal phenotype

no abnormal phenotype detected ( J:5225 )

• mutant mice have normal saccular sensory epithelium unlike most other mutations producing deafness

behavior/neurological

abnormal maternal nurturing ( J:5225 )