Phenotypes associated with this allele

• Allele Symbol: Ptpn6^me-2J
• Allele Name: motheaten 2 Jackson
• Allele ID: MGI:1856501
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ptpn6^me-2J/Ptpn6^me-2J	Not Specified	MGI:4451210

Genotype
MGI:4451210

hm1

• Allelic Composition: Ptpn6^me-2J/Ptpn6^me-2J
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality ( J:5579 )

• high mortality before weaning

pigmentation

abnormal skin pigmentation ( J:5579 )

• recognized at 3 to 4 days of age by patchy absence of skin pigment

integument

abnormal coat appearance ( J:5579 )

• patchy absence of hair as the coat appears gives mice a motheaten appearance

focal hair loss ( J:5579 )

• mice appear "moth-eaten"

skin lesions ( J:5579 )

• rapidly progressing lesions develop on the feet by 3 weeks of age

• as early as 2 days after birth abscesses appear on the skin, rupture and begin to heal in 24 hrs

abnormal skin pigmentation ( J:5579 )

• recognized at 3 to 4 days of age by patchy absence of skin pigment