Phenotypes associated with this allele

• Allele Symbol: Grid2^ho-8J
• Allele Name: hotfoot 8 Jackson
• Allele ID: MGI:1856504
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grid2^ho-8J/Grid2^ho-8J	B10.D2/nSnJ	MGI:3719915

Genotype
MGI:3719915

hm1

• Allelic Composition: Grid2^ho-8J/Grid2^ho-8J
• Genetic Background: B10.D2/nSnJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

impaired balance ( J:155927 )

• due to muscle spasms

abnormal locomotor activation ( J:155927 )

abnormal locomotor coordination ( J:155927 )

abnormal gait ( J:155927 )

• at 4 weeks, mice exhibit a quick patting motion of their feet

muscle

muscle spasm ( J:155927 )

• at 6 to 8 weeks, mice develop a whole-body twitching motion

• spasms result in temporary loss of balance

• compensatory limb splaying is observed

reproductive system

reduced female fertility ( J:155927 )

♀

reduced male fertility ( J:155927 )

♂