All Phenotypes Grid2<ho-8J> MGI Mouse

About Help FAQ

Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Grid2^ho-8J
hotfoot 8 Jackson
MGI:1856504

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Grid2^ho-8J/Grid2^ho-8J	B10.D2/nSnJ	MGI:3719915

Allelic Composition	Grid2^ho-8J/Grid2^ho-8J
Genetic Background	B10.D2/nSnJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grid2^ho-8J mutation (0 available); any Grid2 mutation (85 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

impaired balance ( J:155927 )

• due to muscle spasms

abnormal locomotor activation ( J:155927 )

abnormal locomotor coordination ( J:155927 )

abnormal gait ( J:155927 )

• at 4 weeks, mice exhibit a quick patting motion of their feet

muscle

muscle spasm ( J:155927 )

• at 6 to 8 weeks, mice develop a whole-body twitching motion

• spasms result in temporary loss of balance

• compensatory limb splaying is observed

reproductive system

reduced female fertility ( J:155927 )

reduced male fertility ( J:155927 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24