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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		KitW-n
Nagoya dominant spotting
MGI:1856512
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		KitW-n/KitW-n Not Specified MGI:3055568
ht2
 		KitW-n/Kit+ involves: WB MGI:3813823
ht3
 		KitW-n/Kit+ Not Specified MGI:3055567
ht4
 		KitW-n/KitW involves: WB MGI:3813821


Genotype
MGI:3055568
hm1
Allelic
Composition		 KitW-n/KitW-n
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-n mutation (0 available); any Kit mutation (182 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
absent coat pigmentation ( J:12107 )
• signature white coat with black eyes

hematopoietic system
decreased mast cell number ( J:12107 )
• none observed in skin at 5 days of age

immune system
decreased mast cell number ( J:12107 )
• none observed in skin at 5 days of age

integument
absent coat pigmentation ( J:12107 )
• signature white coat with black eyes




Genotype
MGI:3813823
ht2
Allelic
Composition		 KitW-n/Kit+
Genetic
Background		 involves: WB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-n mutation (0 available); any Kit mutation (182 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation

integument




Genotype
MGI:3055567
ht3
Allelic
Composition		 KitW-n/Kit+
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW-n mutation (0 available); any Kit mutation (182 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
diluted coat color ( J:12107 )
• typical dilution of pigmented areas not observed
irregular coat pigmentation ( J:12107 )
• extensive depigmented areas lacking a defined pattern

integument
diluted coat color ( J:12107 )
• typical dilution of pigmented areas not observed
irregular coat pigmentation ( J:12107 )
• extensive depigmented areas lacking a defined pattern




Genotype
MGI:3813821
ht4
Allelic
Composition		 KitW-n/KitW
Genetic
Background		 involves: WB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
KitW mutation (10 available); any Kit mutation (182 available)
KitW-n mutation (0 available); any Kit mutation (182 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased mast cell number ( J:27513 )
• mice exhibit no mast cells in the skin
abnormal mast cell physiology ( J:27513 )
• mast cells do not survive co-culture with fibroblast cells and exhibit impaired attachment

hematopoietic system
decreased mast cell number ( J:27513 )
• mice exhibit no mast cells in the skin
abnormal mast cell physiology ( J:27513 )
• mast cells do not survive co-culture with fibroblast cells and exhibit impaired attachment

pigmentation
absent coat pigmentation ( J:27513 )
• mice are black-eyed with white coats

integument
absent coat pigmentation ( J:27513 )
• mice are black-eyed with white coats




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory