All Phenotypes Kit<W-rio> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Kit^W-rio
dominant spotting rio
MGI:1856516

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kit^W-rio/Kit^W-rio	DBA/2-Kit^W-rio	MGI:3813876
ht2	Kit^W-rio/Kit⁺	DBA/2-Kit^W-rio	MGI:3813877
ht3	Kit^W-rio/Kit⁺	involves: C57BL/6 * DBA/2	MGI:3813878

Allelic Composition	Kit^W-rio/Kit^W-rio
Genetic Background	DBA/2-Kit^W-rio

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-rio mutation (0 available); any Kit mutation (182 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

perinatal lethality, complete penetrance ( J:29400 )

• mice die in late gestation of shortly after birth

hematopoietic system

macrocytic anemia ( J:29400 )

Allelic Composition	Kit^W-rio/Kit⁺
Genetic Background	DBA/2-Kit^W-rio

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-rio mutation (0 available); any Kit mutation (182 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

pigmentation

white spotting ( J:29400 )

• mice exhibit an extensively white coat with few pigmented hairs

integument

white spotting ( J:29400 )

• mice exhibit an extensively white coat with few pigmented hairs

Allelic Composition	Kit^W-rio/Kit⁺
Genetic Background	involves: C57BL/6 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kit^W-rio mutation (0 available); any Kit mutation (182 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

reversion by mitotic recombination ( J:29400 )

• 3.6% of mice exhibit revertant pigmented patches with most revertant cells exhibiting loss of heterozygosity following mitotic recombination between the centromere and Kit locus

pigmentation

white spotting ( J:29400 )

• mice exhibit an extensively white coat with few pigmented hairs

integument

white spotting ( J:29400 )

• mice exhibit an extensively white coat with few pigmented hairs

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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