Phenotypes associated with this allele

• Allele Symbol: Kit^W-rio
• Allele Name: dominant spotting rio
• Allele ID: MGI:1856516
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kit^W-rio/Kit^W-rio	DBA/2-Kit^W-rio	MGI:3813876
ht2	Kit^W-rio/Kit^+	DBA/2-Kit^W-rio	MGI:3813877
ht3	Kit^W-rio/Kit^+	involves: C57BL/6 * DBA/2	MGI:3813878

Genotype
MGI:3813876

hm1

• Allelic Composition: Kit^W-rio/Kit^W-rio
• Genetic Background: DBA/2-Kit^W-rio

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality, complete penetrance ( J:29400 )

• mice die in late gestation of shortly after birth

hematopoietic system

macrocytic anemia ( J:29400 )

Genotype
MGI:3813877

ht2

• Allelic Composition: Kit^W-rio/Kit⁺
• Genetic Background: DBA/2-Kit^W-rio

pigmentation

white spotting ( J:29400 )

• mice exhibit an extensively white coat with few pigmented hairs

integument

white spotting ( J:29400 )

• mice exhibit an extensively white coat with few pigmented hairs

Genotype
MGI:3813878

ht3

• Allelic Composition: Kit^W-rio/Kit⁺
• Genetic Background: involves: C57BL/6 * DBA/2

normal phenotype

reversion by mitotic recombination ( J:29400 )

• 3.6% of mice exhibit revertant pigmented patches with most revertant cells exhibiting loss of heterozygosity following mitotic recombination between the centromere and Kit locus

pigmentation

white spotting ( J:29400 )

• mice exhibit an extensively white coat with few pigmented hairs

integument

white spotting ( J:29400 )

• mice exhibit an extensively white coat with few pigmented hairs