Phenotypes associated with this allele

• Allele Symbol: Reln^rl-2J
• Allele Name: reeler 2 Jackson
• Allele ID: MGI:1856543
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Reln^rl-2J/Reln^rl-2J	involves: C3H * C57BL/6J * DBA/2J	MGI:3784587

Genotype
MGI:3784587

hm1

• Allelic Composition: Reln^rl-2J/Reln^rl-2J
• Genetic Background: involves: C3H * C57BL/6J * DBA/2J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal retina rod bipolar cell morphology ( J:71970 )

• density of cells is decreased, indicating a decreased number of rod bipolar cells compared to controls

abnormal retina inner nuclear layer morphology ( J:71970 )

• number of synaptic endings (with lobular appendage morphology) in S1 layer of ICL in controls is significantly higher than in mutants

• number of synaptic endings in S2 and S3 are significantly increased in mutants compared to controls

• in S4 and S5, total number of type AII dendrites is reduced relative to controls

abnormal cone electrophysiology ( J:71970 )

• cone mediated-responses are reduced in amplitude and delayed in mutants; difference compared to wild-type cone function is not as great as differences in rod function

abnormal rod electrophysiology ( J:71970 )

• amplitude of a-wave of ERG in response to bright light flash is smaller than in controls while the b-wave is significantly reduced

• oscillatory potentials (OPs) are reduced in amplitude

nervous system

abnormal retina rod bipolar cell morphology ( J:71970 )

• density of cells is decreased, indicating a decreased number of rod bipolar cells compared to controls