All Phenotypes t<6> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

t⁶
t, 6
MGI:1856562

Summary

14 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	t⁶/t^h17	Not Specified	MGI:4821281
ht2	t^h20/t⁶	Not Specified	MGI:4868622
ht3	t⁶/t^hr4	Not Specified	MGI:5465156
ht4	t⁶/t^h57	Not Specified	MGI:5465161
ht5	t^hr1/t⁶	Not Specified	MGI:5465172
cx6	T^30H/T⁺ t⁶/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719859
cx7	T^32H/T⁺ t⁶/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719860
cx8	T^36H/T⁺ t⁶/t⁺	involves: 101/H * C3H/HeH * TFH	MGI:3719862
cx9	t⁶/Tagap^tm1Bgh	involves: BALB/c * BTBR/TF * FVB/N	MGI:3639742
cx10	T^29H/T⁺ t⁶/t⁺	involves: BALB/c * TFH	MGI:3719858
cx11	T^4J/t⁶	involves: BALB/cBy	MGI:4830251
cx12	T^5J/t⁶	involves: C57BL/6J	MGI:4830536
cx13	T/t⁶	Not Specified	MGI:3663265
cx14	t⁶/t⁺ Tg(Ace-Nme3)H17Bgh/0	Not Specified	MGI:5319402

Allelic Composition	t⁶/t^h17
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t⁶ mutation (0 available); any t mutation (19 available)
t^h17 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality ( J:5889 )

Allelic Composition	t^h20/t⁶
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t⁶ mutation (0 available); any t mutation (19 available)
t^h20 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality ( J:5889 )

Allelic Composition	t⁶/t^hr4
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t⁶ mutation (0 available); any t mutation (19 available)
t^hr4 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:169366 )

• no mice are produced

Allelic Composition	t⁶/t^h57
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t⁶ mutation (0 available); any t mutation (19 available)
t^h57 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:169366 )

• no mice are produced

Allelic Composition	t^hr1/t⁶
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t⁶ mutation (0 available); any t mutation (19 available)
t^hr1 mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:183153 )

• no mice produced

Allelic Composition	T^30H/T⁺ t⁶/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^30H mutation (0 available); any T mutation (59 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	T^32H/T⁺ t⁶/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^32H mutation (0 available); any T mutation (59 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	T^36H/T⁺ t⁶/t⁺
Genetic Background	involves: 101/H * C3H/HeH * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^36H mutation (0 available); any T mutation (59 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	t⁶/Tagap^tm1Bgh
Genetic Background	involves: BALB/c * BTBR/TF * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t⁶ mutation (0 available); any t mutation (19 available)
Tagap^tm1Bgh mutation (0 available); any Tagap mutation (22 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal meiosis ( J:100859 )

abnormal male meiosis ( J:100859 )

• reduced transmission found for sperm bearing t⁶

abnormal sperm motility ( J:100859 )

• compromised sperm motility is inferred as overexpression of Tagap1 results in greater than normal t⁶ haplotype transmission

asthenozoospermia ( J:100859 )

cellular

abnormal meiosis ( J:100859 )

abnormal male meiosis ( J:100859 )

• reduced transmission found for sperm bearing t⁶

abnormal sperm motility ( J:100859 )

• compromised sperm motility is inferred as overexpression of Tagap1 results in greater than normal t⁶ haplotype transmission

asthenozoospermia ( J:100859 )

Allelic Composition	T^29H/T⁺ t⁶/t⁺
Genetic Background	involves: BALB/c * TFH

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^29H mutation (0 available); any T mutation (59 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:62655 )

• the transmission ratio distortion associated with t⁶ is increased

Allelic Composition	T^4J/t⁶
Genetic Background	involves: BALB/cBy

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^4J mutation (1 available); any T mutation (59 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:30778 )

Allelic Composition	T^5J/t⁶
Genetic Background	involves: C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T^5J mutation (1 available); any T mutation (59 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

absent tail ( J:78379 )

Allelic Composition	T/t⁶
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
t⁶ mutation (0 available); any t mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

decreased ventral ectodermal ridge size ( J:15081 )

• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 69% of the normal size

embryo

abnormal notochord morphology ( J:15081 )

• the notochord is increased in bulk not only in the distal growth zone (as in T heterozygotes) but in the whole tail, in the cloacal region and even more anteriorly in the lumbar region and has large lumina

• the notochord is present throughout the length of the tail, however it becomes incorporated into the neural tube throughout the tail and often the cloacal region

decreased ventral ectodermal ridge size ( J:15081 )

• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 69% of the normal size

Allelic Composition	t⁶/t⁺ Tg(Ace-Nme3)H17Bgh/0
Genetic Background	Not Specified

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t⁶ mutation (0 available); any t mutation (19 available)
Tg(Ace-Nme3)H17Bgh mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

transmission ratio distortion ( J:183481 )

• the transmission ratio distortion associated with t⁶ is decreased

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