Phenotypes associated with this allele

• Allele Symbol: t^w2
• Allele Name: t, wild 2
• Allele ID: MGI:1856569
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	t^w2/t^w2	Not Specified	MGI:3040931
ht2	t^w82/t^w2	Not Specified	MGI:4437730

Genotype
MGI:3040931

hm1

• Allelic Composition: t^w2/t^w2
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

seminiferous tubule degeneration ( J:89468 )

♂ • many degenerating tubules with no germ cells are found in homozygotes

♂ • phagocytosis of abnormal spermatids by Sertoli cells is seen

reproductive system

teratozoospermia ( J:89468 )

♂ • the nuclear envelope becomes discontinuous in some elongating spermatids and an overproliferation of disorganized microtubules is seen in homozygotes

abnormal manchette morphology ( J:89468 )

♂ • overproliferation of disorganized microtubules is observed

seminiferous tubule degeneration ( J:89468 )

♂ • many degenerating tubules with no germ cells are found in homozygotes

♂ • phagocytosis of abnormal spermatids by Sertoli cells is seen

male infertility ( J:89468 )

♂ • males are sterile

cellular

teratozoospermia ( J:89468 )

♂ • the nuclear envelope becomes discontinuous in some elongating spermatids and an overproliferation of disorganized microtubules is seen in homozygotes

abnormal manchette morphology ( J:89468 )

♂ • overproliferation of disorganized microtubules is observed

Genotype
MGI:4437730

ht2

• Allelic Composition: t^w82/t^w2
• Genetic Background: Not Specified

reproductive system

reduced male fertility ( J:97017 )

♂