mortality/aging
• embryos develop only to the two-layered egg cylinder stage, dying within 5 days after implantation
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embryo
• post-implantation growth of the embryo is markedly reduced
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• the expected association of trophectoderm with the uterine decidua fails to form
• an abnormal trophectoderm does not inhibit embryonic growth to the two-layered egg cylinder stage
• growth abnormalities seen in the embryo can be attributed to a defective trophectoderm
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• the expected association of ectoplacental cone with the uterine decidua does not occur
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cellular
• post-implantation growth of the embryo is markedly reduced
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