Phenotypes associated with this allele

• Allele Symbol: Al
• Allele Name: alopecia
• Allele ID: MGI:1856590
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Al/Al	involves: C57BL/10J * STOCK Sgk3^fz	MGI:2654866
ht2	Al/Al^+	involves: C57BL/10J * STOCK Sgk3^fz	MGI:2654868

Genotype
MGI:2654866

hm1

• Allelic Composition: Al/Al
• Genetic Background: involves: C57BL/10J * STOCK Sgk3^fz

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

integument

abnormal coat appearance ( J:237 )

• at weaning only guard or awl hair types are present

alopecia ( J:237 )

• hair loss first noticeable between 25 and 30 days of age

• at moulting, mice lose all hair except for a few guard hairs

• after moulting other hair types are replaced but appear patchy

focal hair loss ( J:237 )

• hair grows in after moult cycles but appears patchy

Genotype
MGI:2654868

ht2

• Allelic Composition: Al/Al⁺
• Genetic Background: involves: C57BL/10J * STOCK Sgk3^fz

integument

alopecia ( J:237 )

• mice do not have a full coat but have distinctly more hair than homozygotes

• mice lose all but guard hairs on the ventrum

abnormal hair texture ( J:237 )

• the dorsal coat is not as smooth as wild-type mice