cardiovascular system
• seen during embryonic development on the dorsal side of the toes, especially on one or both hind feet
|
homeostasis/metabolism
limbs/digits/tail
• digits are flexed in mice with affected feet
|
syndactyly
(
J:5810
)
• only soft tissue fusions
|
skeleton
• results in shortened and distorted phalanges
|
vision/eye
cornea opacity
(
J:5810
)
• common to see at least one eye affected in adults
|
microphthalmia
(
J:5810
)
• common to see at least one eye affected in adults
• clearly evident in newborn mice
|
• clearly evident in newborn mice
|
integument
fetal bleb
(
J:5810
)
• seen as early as E12, as distended, enucleated mesenchymal cells
|