mortality/aging
pigmentation
• with agouti coat resembles homozygous chinchilla, dark, sooty grey
• the phaeomelanin pigment band on the hairs of agouti mice is white
• black eumelanin pigment is unaffected, in contrast to effect of chinchilla
• with nonagouti coat is normal but white hairs replace yellow on and around ears and genitalia
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growth/size/body
• mice weigh 10% less than normal sibs at birth, 30% less by 3 weeks, 20% less by 8 weeks of age
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reproductive system
integument
• with agouti coat resembles homozygous chinchilla, dark, sooty grey
• the phaeomelanin pigment band on the hairs of agouti mice is white
• black eumelanin pigment is unaffected, in contrast to effect of chinchilla
• with nonagouti coat is normal but white hairs replace yellow on and around ears and genitalia
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