Phenotypes associated with this allele

• Allele Symbol: Mpzl3^ruf
• Allele Name: rough fur
• Allele ID: MGI:1856627
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mpzl3^ruf/Mpzl3^ruf	C3H/HeJ-Mpzl3^ruf	MGI:3774562

Genotype
MGI:3774562

hm1

• Allelic Composition: Mpzl3^ruf/Mpzl3^ruf
• Genetic Background: C3H/HeJ-Mpzl3^ruf

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal sebaceous gland morphology ( J:69953 )

enlarged sebaceous gland ( J:69953 )

• Sudan IV staining shows glands are larger in mutant mice than in controls

abnormal sebaceous gland physiology ( J:69953 )

abnormal sebaceous lipid secretion ( J:69953 )

• EM analysis shows sebaceous gland lipid droplets are denser in mutants than in controls

• may be a model system for hyperlipogenesis

integument

abnormal sebaceous gland morphology ( J:69953 )

enlarged sebaceous gland ( J:69953 )

• Sudan IV staining shows glands are larger in mutant mice than in controls

abnormal sebaceous gland physiology ( J:69953 )

abnormal sebaceous lipid secretion ( J:69953 )

• EM analysis shows sebaceous gland lipid droplets are denser in mutants than in controls

• may be a model system for hyperlipogenesis

abnormal coat/ hair morphology ( J:14266 )

• NORMAL: hair follicle structure and distribution is normal

abnormal coat appearance ( J:14266 )

abnormal hair texture ( J:14266 )

brittle hair ( J:14266 , J:69953 )

• hair breaks off at 13-50 days of age (J:69953)

disheveled coat ( J:14266 )

abnormal hair shaft morphology ( J:14266 )

abnormal skin morphology ( J:14266 )

abnormal epidermis stratum corneum morphology ( J:14266 )

hyperkeratosis ( J:14266 )

• condition is mild