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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Gsdma3Bsk
bareskin
MGI:1856680
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Gsdma3Bsk/Gsdma3Bsk Not Specified MGI:2658847
ht2
Gsdma3Bsk/Gsdma3+ Not Specified MGI:2658842


Genotype
MGI:2658847
hm1
Allelic
Composition
Gsdma3Bsk/Gsdma3Bsk
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gsdma3Bsk mutation (1 available); any Gsdma3 mutation (26 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• starting at ~2 months of age, some homozygotes develop significant corneal opacity

reproductive system
N
• homozygotes are viable and fertile

integument
• adults homozygotes are nearly bare except for some hair on the snout
• hair loss is first evident at 3 weeks of age
• by 3 weeks of age, homozygotes display a sparse coat that becomes progressively thinner with age
• at ~2 weeks of age, homozygotes display folding of the skin
• at ~2 weeks of age, homozygotes are recognizable by the appearance of thickened skin




Genotype
MGI:2658842
ht2
Allelic
Composition
Gsdma3Bsk/Gsdma3+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gsdma3Bsk mutation (1 available); any Gsdma3 mutation (26 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
vision/eye
• starting at ~2 months of age, some heterozygotes develop significant corneal opacity

integument
• adults heterozygotes are nearly bare except for some hair on the snout
• hair loss is first evident at 3 weeks of age
• by 3 weeks of age, heterozygotes display a sparse coat that becomes progressively thinner with age
• at ~2 weeks of age, heterozygotes display folding of the skin
• at ~2 weeks of age, heterozygotes are recognizable by the appearance of thickened skin





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory