Phenotypes associated with this allele

• Allele Symbol: Dsg3^bal
• Allele Name: balding
• Allele ID: MGI:1856692
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Dsg3^bal/Dsg3^bal	C57BL/6J-Dsg3^bal/J	MGI:2175833

Genotype
MGI:2175833

hm1

• Allelic Composition: Dsg3^bal/Dsg3^bal
• Genetic Background: C57BL/6J-Dsg3^bal/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:13702 )

immune system

cutaneous mastocytosis ( J:18223 )

• increased mast cell number in the skin

increased IgE level ( J:18223 )

• serum levels increased

hematopoietic system

cutaneous mastocytosis ( J:18223 )

• increased mast cell number in the skin

increased IgE level ( J:18223 )

• serum levels increased

integument

abnormal hair growth ( J:13702 )

alopecia ( J:13702 )

• adults with bare patches on top of the head and other areas of the body

sparse hair ( J:13702 )

• hair loss evident prior to weaning

abnormal hair follicle morphology ( J:42792 )

• separation of the inner and outer root sheaths of anagen follicles

blistering ( J:42792 )

• vesicles form on the foot pads and, rarely, the interfollicular epidermis

• blistering is very evident

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
pemphigus vulgaris		DOID:0060851	OMIM:169610	J:42792