About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		th49
t, Harwell 49
MGI:1856742
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Nme3tm1Bgh/Nme3+
th49/t+ 		involves: 129S1/Sv MGI:5319401
cx2
 		Fgd2tm1Bgh/Fgd2+
th49/t+ 		involves: BTBR MGI:3700705
cx3
 		th49/t+
Tg(Ace-Tiam2)C1L1Bgh/0 		involves: C57BL/6J MGI:6360723
cx4
 		th49/t+
Tg(Ace-Tiam2)C1L2Bgh/0 		involves: C57BL/6J MGI:6360724


Genotype
MGI:5319401
cx1
Allelic
Composition		 Nme3tm1Bgh/Nme3+
th49/t+
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nme3tm1Bgh mutation (0 available); any Nme3 mutation (10 available)
th49 mutation (1 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:183481 )
• mice exhibit increased transmission of the t-haplotype compared with wild-type mice




Genotype
MGI:3700705
cx2
Allelic
Composition		 Fgd2tm1Bgh/Fgd2+
th49/t+
Genetic
Background		 involves: BTBR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgd2tm1Bgh mutation (0 available); any Fgd2 mutation (34 available)
th49 mutation (1 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:117419 )
• mice transmitted the th49 allele to only 35% of their offspring compared to a transmission rate of 47% for mice without the Fgd2 mutant allele




Genotype
MGI:6360723
cx3
Allelic
Composition		 th49/t+
Tg(Ace-Tiam2)C1L1Bgh/0
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ace-Tiam2)C1L1Bgh mutation (0 available)
th49 mutation (1 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:273736 )
• mice exhibit reduced transmission of th49 compared with wild-type mice




Genotype
MGI:6360724
cx4
Allelic
Composition		 th49/t+
Tg(Ace-Tiam2)C1L2Bgh/0
Genetic
Background		 involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ace-Tiam2)C1L2Bgh mutation (0 available)
th49 mutation (1 available); any t mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
transmission ratio distortion ( J:273736 )
• mice exhibit reduced transmission of th49 compared with wild-type mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory