Phenotypes associated with this allele

• Allele Symbol: gp
• Allele Name: gaping lids
• Allele ID: MGI:1856887
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	gp/gp	involves: C57BL/6-Usp14^ax-J	MGI:2175045

Genotype
MGI:2175045

hm1

• Allelic Composition: gp/gp
• Genetic Background: involves: C57BL/6-Usp14^ax-J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Eyelid phenotype, scanning electron micrographs and histological cross-section of E16-E18 gp/gp and normal fetuses.

vision/eye

cornea opacity ( J:211 , J:62514 )

• the eyes of homozygous mutant mice become opaque with age (J:211)

• this phenotype was originally reported to have full penetrance (J:211) (J:62514)

• Background Sensitivity: penetrance in linkage studies is incomplete and variably affected by genetic background (J:62514)

enlarged lens ( J:211 )

• from 15 days of gestation onward the lens is twice the size of C57BL/6 controls

absent eyelids ( J:62514 )

• on day 16 of gestation upper and lower eyelid tissue is deficient

• surface periderm cell behavior appears abnormal

eyelids open at birth ( J:211 )

blindness ( J:211 )

• in mature adults