Phenotypes associated with this allele

• Allele Symbol: Wnt7a^px
• Allele Name: postaxial hemimelia
• Allele ID: MGI:1857009
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Wnt7a^px/Wnt7a^px	involves: STOCK Sox18^Ra	MGI:2174808

Genotype
MGI:2174808

hm1

• Allelic Composition: Wnt7a^px/Wnt7a^px
• Genetic Background: involves: STOCK Sox18^Ra

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

limbs/digits/tail

oligodactyly ( J:112 )

• there may be absence of digits 5, 4, and sometimes 3 on the forelimbs

• digit 5 may be absent on the hindlimbs

abnormal forelimb morphology ( J:112 )

• forelimbs are regularly affected

abnormal ulna morphology ( J:112 )

• reduction or absence of the ulna

abnormal hindlimb morphology ( J:112 )

• hindlimbs are usually normal, but digit 5 may be absent, and occasionally the fibula is reduced

short fibula ( J:112 )

• occasionally the fibula is reduced

reproductive system

female infertility ( J:112 )

♀

male infertility ( J:112 )

♂

skeleton

abnormal ulna morphology ( J:112 )

• reduction or absence of the ulna

short fibula ( J:112 )

• occasionally the fibula is reduced

scapular bone foramen ( J:112 )

• a large oval foramen is present in the scapula

increased rib number ( J:112 )

• mice with more severely affected limbs tend to have an extra pair of ribs

decreased presacral vertebrae number ( J:112 )

• mice with more severely affected limbs tend to have a slight reduction in the number of presacral vertebrae

embryo

abnormal Mullerian duct morphology ( J:112 )

• anomalies of the Mullerian ducts in both sexes