skeleton
• anomalies likely result from retarded growth of the mandibular condyle, maxillary sutures, and connective tissue of the dental pulp
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• the sternum is short, broad, unsegmented
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• abnormalities of the sternum appear to result from retarded growth of the ribs which fails to bring the bilateral sternal bands into close association during development
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short sternum
(
J:277
)
wide sternum
(
J:277
)
• one more than normal
|
• results in sharp kinks in the thoracic or lumbar region
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limbs/digits/tail
• the tail is tightly coiled at birth but "opens" as the mouse ages leaving the tail bent into various angles
• compared to other areas of the tail, the tail is thickened where angles occur
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mortality/aging
• 24 per cent of mutant mice are dead at birth and more die by weaning but a few survive into adulthood
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growth/size/body
• anomalies likely result from retarded growth of the mandibular condyle, maxillary sutures, and connective tissue of the dental pulp
|
• noticeable at birth
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reproductive system
• few among the mutants that survive as adults breed
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craniofacial
• anomalies likely result from retarded growth of the mandibular condyle, maxillary sutures, and connective tissue of the dental pulp
|