Phenotypes associated with this allele

• Allele Symbol: vc
• Allele Name: vacillans
• Allele ID: MGI:1857085
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	vc/vc	DBA/1-vc	MGI:3851109

Genotype
MGI:3851109

hm1

• Allelic Composition: vc/vc
• Genetic Background: DBA/1-vc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased survivor rate ( J:297 )

postnatal lethality, incomplete penetrance ( J:297 )

• peak mortality is at weaning age but some survive and have a normal lifespan

behavior/neurological

decreased aggression towards mice ( J:297 )

tremors ( J:297 )

• by 14 days of age violent tremors occur when mice walk

• less marked in older mice

abnormal gait ( J:297 )

• tremors occur as mice walk

• hindquarters sway

• as mice age a duck-like gait is observed; tail is kept upright and rigid

abnormal maternal nurturing ( J:297 )

♀

growth/size/body

decreased body size ( J:297 )

• mice are smaller than normal siblings

muscle

muscle weakness ( J:297 )

• muscular strength is half of normal mice

reproductive system

delayed male fertility ( J:297 )

• sexual maturity does not occur in males before five and a half months of age

hearing/vestibular/ear

deafness ( J:297 )

• Background Sensitivity: hearing deficiency is detected between 45 and 60 days of age