All Phenotypes Mip<Cat-Lop> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mip^Cat-Lop
cataract lens opacity
MGI:1857105

Summary

2 genotypes

Allelic Composition	Mip^Cat-Lop/Mip^Cat-Lop
Genetic Background	involves: STOCK Rb(6.15)1Ald

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mip^Cat-Lop mutation (1 available); any Mip mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

abnormal lens fiber morphology ( J:6702 )

• no regular arrangement of layers of lens fibers

cataract ( J:6702 )

• opaque lenses

small lens ( J:6702 )

microphthalmia ( J:6702 )

• very small eyes

Allelic Composition	Mip^Cat-Lop/Mip⁺
Genetic Background	involves: STOCK Rb(6.15)1Ald

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mip^Cat-Lop mutation (1 available); any Mip mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

vision/eye

total cataract ( J:6702 )

• total lens opacity; in rare few the opacity is less than total

• opacity is present at the time the eyes first open (P12)

microphthalmia ( J:6702 )

• slightly reduced eye size; less severe than displayed by homozygous mutant mice

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
cataract 15 multiple types		DOID:0110251	OMIM:615274	J:31574

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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