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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ighdtm1Cgn
targeted mutation 1, University of Cologne
MGI:1857186
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ighdtm1Cgn/Ighdtm1Cgn involves: 129P2/OlaHsd * C57BL/6 MGI:2179107


Genotype
MGI:2179107
hm1
Allelic
Composition		 Ighdtm1Cgn/Ighdtm1Cgn
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ighdtm1Cgn mutation (2 available); any Ighd mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal immune system physiology ( J:64281 )
• delayed antibody affinity maturation
• no defect in lymphocyte development
• normal response to T cell-dependent and -independent antigens
decreased IgE level ( J:64281 )
• decreased IgE serum concentrations

hematopoietic system
decreased IgE level ( J:64281 )
• decreased IgE serum concentrations




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory