Phenotypes associated with this allele

• Allele Symbol: Ednrb^s-1Chlc
• Allele Name: chlorambucil 1Chlc
• Allele ID: MGI:1857326
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Ednrb^s-1Chlc/Ednrb^s-1Chlc	involves: 101/Rl * C3H/Rl	MGI:3777966
ht2	Ednrb^s/Ednrb^s-1Chlc	involves: 101/Rl * C3H/Rl	MGI:3777965

Genotype
MGI:3777966

hm1

• Allelic Composition: Ednrb^s-1Chlc/Ednrb^s-1Chlc
• Genetic Background: involves: 101/Rl * C3H/Rl

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

postnatal lethality, incomplete penetrance ( J:10322 , J:16291 , J:44601 , J:100221 )

• most homozygotes die at 20-38 days of age (J:10322)

• juvenile lethality (J:44601)

• juvenile lethality (J:100221)

digestive/alimentary system

megacolon ( J:10322 , J:44601 , J:100221 )

pigmentation

white spotting ( J:10322 , J:16291 , J:44601 , J:100221 )

• pigmented areas of fur comprise only ~10% of the surface area (J:10322)

• greater than 90% white spotting (J:100221)

integument

white spotting ( J:10322 , J:16291 , J:44601 , J:100221 )

• pigmented areas of fur comprise only ~10% of the surface area (J:10322)

• greater than 90% white spotting (J:100221)

Genotype
MGI:3777965

ht2

• Allelic Composition: Ednrb^s/Ednrb^s-1Chlc
• Genetic Background: involves: 101/Rl * C3H/Rl

pigmentation

white spotting ( J:100221 )

• similar to Ednrb^s homozygotes

integument

white spotting ( J:100221 )

• similar to Ednrb^s homozygotes