Phenotypes associated with this allele

• Allele Symbol: Ebp^Td-ho
• Allele Name: tattered Hokkaido
• Allele ID: MGI:1857338
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Ebp^Td-ho/Ebp^+	involves: C57BL/6J * M. spretus	MGI:5009021
ot2	Ebp^Td-ho/Y	(CKH.Cg-Ebp^Td-ho x NJL)F1	MGI:5009024
ot3	Ebp^Td-ho/Y	involves: C57BL/6J * M. spretus	MGI:5009023

Genotype
MGI:5009021

ht1

• Allelic Composition: Ebp^Td-ho/Ebp⁺
• Genetic Background: involves: C57BL/6J * M. spretus

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

decreased body size ( J:42173 )

♀ • females of this genotype tend to be smaller

decreased body weight ( J:42173 )

♀ • at weaning

integument

hyperkeratosis ( J:42173 )

♀ • patchy scarring of skin from one week of age

mortality/aging

decreased survivor rate ( J:42173 )

♀

Genotype
MGI:5009024

ot2

• Allelic Composition: Ebp^Td-ho/Y
• Genetic Background: (CKH.Cg-Ebp^Td-ho x NJL)F1

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:42173 )

♂ • on this mixed background dead mutant males were observed from E12.5 through E14.5

embryo

abnormal embryonic hematopoiesis ( J:60400 )

♂

abnormal embryonic erythropoiesis ( J:60400 )

♂

hematopoietic system

abnormal embryonic hematopoiesis ( J:60400 )

♂

abnormal embryonic erythrocyte morphology ( J:60400 )

♂ • increased apoptosis of yolk sac-derived erythrocytes in E12.5 embryos

♂ • diminished numbers of anucleated erythrocytes observed in E12.5 embryos

abnormal embryonic erythropoiesis ( J:60400 )

♂

Genotype
MGI:5009023

ot3

• Allelic Composition: Ebp^Td-ho/Y
• Genetic Background: involves: C57BL/6J * M. spretus

mortality/aging

prenatal lethality, complete penetrance ( J:42173 )

♂ • male mutants die between E12.5 and E14.5