Phenotypes associated with this allele

• Allele Symbol: Mstn^Cmpt
• Allele Name: compact
• Allele ID: MGI:1857404
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mstn^Cmpt/Mstn^Cmpt	BEH	MGI:5529127
ht2	Mstn^Cmpt/Mstn^+	either: HCI or HCR	MGI:5529108

Genotype
MGI:5529127

hm1

• Allelic Composition: Mstn^Cmpt/Mstn^Cmpt
• Genetic Background: BEH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

muscle

increased skeletal muscle mass ( J:119757 )

impaired skeletal muscle contractility ( J:119757 )

♀ • 2 month old females show significantly lower specific force measurements compared with wild-type controls

Genotype
MGI:5529108

ht2

• Allelic Composition: Mstn^Cmpt/Mstn⁺
• Genetic Background: either: HCI or HCR

muscle

abnormal muscle morphology ( J:43299 )

increased skeletal muscle mass ( J:43299 )

• phenotype is more distinct among males

• hypermuscularity is variable but always greater than found in wild-type mice

• variable expression depends on presence/absence of at least one modifier

growth/size/body

abnormal body composition ( J:43299 )

increased body weight ( J:43299 )

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
myostatin-related muscle hypertrophy		DOID:0111072	OMIM:614160	J:43299