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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Emx1tm1Jlr
targeted mutation 1, John Rubenstein
MGI:1857433
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Emx1tm1Jlr/Emx1tm1Jlr involves: 129X1/SvJ * C57BL/6 MGI:2179764
ht2
 		Emx1tm1Jlr/Emx1+ involves: 129X1/SvJ * C57BL/6 MGI:2179767


Genotype
MGI:2179764
hm1
Allelic
Composition		 Emx1tm1Jlr/Emx1tm1Jlr
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1tm1Jlr mutation (1 available); any Emx1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
reproductive system phenotype ( J:35060 )
N
• homozygous mice are fertile

nervous system
absent corpus callosum ( J:35060 )
• all homozygous mutant mice lack most or all of the corpus collosum; histological analysis revealed a small interhemispheric commissure, which may be residual corpus collosum




Genotype
MGI:2179767
ht2
Allelic
Composition		 Emx1tm1Jlr/Emx1+
Genetic
Background		 involves: 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Emx1tm1Jlr mutation (1 available); any Emx1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal corpus callosum morphology ( J:35060 )
• incomplete penetrance; observed in 5 of 15 heterozygous mice




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory