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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Srd5a1tm1Mahe
targeted mutation 1, Mala Mahendroo
MGI:1857454
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Srd5a1tm1Mahe/Srd5a1tm1Mahe involves: 129S7/SvEvBrd * C57BL/6J MGI:3029374
cx2
Srd5a1tm1Mahe/Srd5a1tm1Mahe
Srd5a2tm1Mahe/Srd5a2tm1Mahe
involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6J MGI:3029378


Genotype
MGI:3029374
hm1
Allelic
Composition
Srd5a1tm1Mahe/Srd5a1tm1Mahe
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srd5a1tm1Mahe mutation (1 available); any Srd5a1 mutation (11 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• 33% of homozygous female mice delivered litters on day 19 of gestation; the remainder exhibited prolonged labor, fetal death and often maternal death
• homozygous female mice that delivered on day 19 of gestation had an average litter size of 3 pups vs. 8 pups in control females




Genotype
MGI:3029378
cx2
Allelic
Composition
Srd5a1tm1Mahe/Srd5a1tm1Mahe
Srd5a2tm1Mahe/Srd5a2tm1Mahe
Genetic
Background
involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Srd5a1tm1Mahe mutation (1 available); any Srd5a1 mutation (11 available)
Srd5a2tm1Mahe mutation (0 available); any Srd5a2 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands

reproductive system
• described as similar to single mutation





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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory