Analysis Tools
mortality/aging
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• die around E12.5
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cardiovascular system
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• small foci of intraparenchymal hemorrhages within the central nervous system are seen in some E11.5 embryos
• E12.5 embryos exhibit extensive hemorrhages within the vertebral canal
• hemorrhages appear to originate within the ganglia of the cranial nerves
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• hemorrhages into the pericardial space, evident at E12.5
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• hemorrhages into peritoneal cavity, evident at E12.5
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• E12.5 embryos exhibit extensive hemorrhages within the ventricle of the central nervous system
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nervous system
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• E12.5 embryos exhibit extensive hemorrhages within the ventricle of the central nervous system
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embryo
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• mutants lack fetal liver hematopoiesis; no erythroid, myeloid, or megakaryocyte elements are seen in livers at E11.5-E12.5
• progenitors for definitive hematopoiesis of either erythroid or myeloid lineages are absent from the yolk sac and liver
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hematopoietic system
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• mutants lack fetal liver hematopoiesis; no erythroid, myeloid, or megakaryocyte elements are seen in livers at E11.5-E12.5
• progenitors for definitive hematopoiesis of either erythroid or myeloid lineages are absent from the yolk sac and liver
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liver/biliary system
pale liver
(
J:31130
)
|
• slight pallor of the liver at E11.5
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homeostasis/metabolism
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• hemorrhages into the pericardial space, evident at E12.5
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