About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		CrygeElo
eye lens obsolescence
MGI:1857599
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		CrygeElo/CrygeElo C3N.Cg-CrygeElo MGI:3582641
hm2
 		CrygeElo/CrygeElo involves: C57BL/6JNga MGI:3582640
ht3
 		CrygeElo/Cryge+ involves: C57BL/6JNga MGI:2175811


Genotype
MGI:3582641
hm1
Allelic
Composition		 CrygeElo/CrygeElo
Genetic
Background		 C3N.Cg-CrygeElo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygeElo mutation (2 available); any Cryge mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens development ( J:1630 )
• lens fiber cells appeared to proliferate normally suggesting that the defect is in lens fiber differentiation and not cell proliferation
abnormal lens fiber morphology ( J:6481 )
• at E12, the central lens fibers do not properly elongate
• these fibers become necrotic by late fetal developmental stages
small lens ( J:6481 )
• by late fetal development stages, the lens is small and deformed




Genotype
MGI:3582640
hm2
Allelic
Composition		 CrygeElo/CrygeElo
Genetic
Background		 involves: C57BL/6JNga
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygeElo mutation (2 available); any Cryge mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens morphology ( J:15383 )
• lens completely degenerates by 30 days of age
abnormal lens development ( J:15383 )
• lens is underdeveloped at birth




Genotype
MGI:2175811
ht3
Allelic
Composition		 CrygeElo/Cryge+
Genetic
Background		 involves: C57BL/6JNga
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygeElo mutation (2 available); any Cryge mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens morphology ( J:15383 )
• lens completely degenerates by 30 days of age
abnormal lens development ( J:15383 )
• lens is underdeveloped at birth




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory