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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		CrygeElo
eye lens obsolescence
MGI:1857599
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		CrygeElo/CrygeElo C3N.Cg-CrygeElo MGI:3582641
hm2
 		CrygeElo/CrygeElo involves: C57BL/6JNga MGI:3582640
ht3
 		CrygeElo/Cryge+ involves: C57BL/6JNga MGI:2175811


Genotype
MGI:3582641
hm1
Allelic
Composition		 CrygeElo/CrygeElo
Genetic
Background		 C3N.Cg-CrygeElo
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygeElo mutation (2 available); any Cryge mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens development ( J:1630 )
• lens fiber cells appeared to proliferate normally suggesting that the defect is in lens fiber differentiation and not cell proliferation
abnormal lens fiber morphology ( J:6481 )
• at E12, the central lens fibers do not properly elongate
• these fibers become necrotic by late fetal developmental stages
small lens ( J:6481 )
• by late fetal development stages, the lens is small and deformed




Genotype
MGI:3582640
hm2
Allelic
Composition		 CrygeElo/CrygeElo
Genetic
Background		 involves: C57BL/6JNga
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygeElo mutation (2 available); any Cryge mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens morphology ( J:15383 )
• lens completely degenerates by 30 days of age
abnormal lens development ( J:15383 )
• lens is underdeveloped at birth




Genotype
MGI:2175811
ht3
Allelic
Composition		 CrygeElo/Cryge+
Genetic
Background		 involves: C57BL/6JNga
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
CrygeElo mutation (2 available); any Cryge mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
abnormal lens morphology ( J:15383 )
• lens completely degenerates by 30 days of age
abnormal lens development ( J:15383 )
• lens is underdeveloped at birth




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory