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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Xicb
X Chromosome controlling element b
MGI:1857664
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		Xicb/Xicc
Xiaf3/Xiaf3+ 		involves: 129X1/SvJ * C57BL/6J * CAST/Ei * CBA/J MGI:3718786
cx2
 		Xicb/Xicc
Xiaf2/Xiaf2+ 		involves: 129X1/SvJ * C57BL/6J * CAST/Ei * CBA/J MGI:3718787


Genotype
MGI:3718786
cx1
Allelic
Composition		 Xicb/Xicc
Xiaf3/Xiaf3+
Genetic
Background		 involves: 129X1/SvJ * C57BL/6J * CAST/Ei * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Xiaf3 mutation (0 available); any Xiaf3 mutation (0 available)
Xicb mutation (0 available); any Xic mutation (1 available)
Xicc mutation (0 available); any Xic mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:76512 )
• carriers are viable and fertile with no gross abnormalities; however significantly more cells than expected have as the active X chromosome the X chromosome carrying the Xceb allele




Genotype
MGI:3718787
cx2
Allelic
Composition		 Xicb/Xicc
Xiaf2/Xiaf2+
Genetic
Background		 involves: 129X1/SvJ * C57BL/6J * CAST/Ei * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Xiaf2 mutation (0 available); any Xiaf2 mutation (0 available)
Xicb mutation (0 available); any Xic mutation (1 available)
Xicc mutation (0 available); any Xic mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal dosage compensation, by inactivation of X chromosome ( J:85407 )
• expression analysis indicates an aberrant pattern of X chromosome inactivation




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory