All Phenotypes Xic<c> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Xic^c
X Chromosome controlling element c
MGI:1857665

Summary

3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Xic^a/Xic^c Xiaf1/Xiaf1⁺	involves: 129X1/SvJ * BALB/cByJ * CAST/Ei	MGI:3718785
cx2	Xic^b/Xic^c Xiaf3/Xiaf3⁺	involves: 129X1/SvJ * C57BL/6J * CAST/Ei * CBA/J	MGI:3718786
cx3	Xic^b/Xic^c Xiaf2/Xiaf2⁺	involves: 129X1/SvJ * C57BL/6J * CAST/Ei * CBA/J	MGI:3718787

Allelic Composition	Xic^a/Xic^c Xiaf1/Xiaf1⁺
Genetic Background	involves: 129X1/SvJ * BALB/cByJ * CAST/Ei

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Xiaf1 mutation (0 available); any Xiaf1 mutation (0 available)
Xic^a mutation (1 available); any Xic mutation (1 available)
Xic^c mutation (0 available); any Xic mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:76512 )

• carriers are viable and fertile with no gross abnormalities; however significantly more cells than expected have as the active X chromosome the X chromosome carrying the Xce^a allele

Allelic Composition	Xic^b/Xic^c Xiaf3/Xiaf3⁺
Genetic Background	involves: 129X1/SvJ * C57BL/6J * CAST/Ei * CBA/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Xiaf3 mutation (0 available); any Xiaf3 mutation (0 available)
Xic^b mutation (0 available); any Xic mutation (1 available)
Xic^c mutation (0 available); any Xic mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

normal phenotype

no abnormal phenotype detected ( J:76512 )

• carriers are viable and fertile with no gross abnormalities; however significantly more cells than expected have as the active X chromosome the X chromosome carrying the Xce^b allele

Allelic Composition	Xic^b/Xic^c Xiaf2/Xiaf2⁺
Genetic Background	involves: 129X1/SvJ * C57BL/6J * CAST/Ei * CBA/J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Xiaf2 mutation (0 available); any Xiaf2 mutation (0 available)
Xic^b mutation (0 available); any Xic mutation (1 available)
Xic^c mutation (0 available); any Xic mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

abnormal dosage compensation, by inactivation of X chromosome ( J:85407 )

• expression analysis indicates an aberrant pattern of X chromosome inactivation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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