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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Smad2tm2Enl
targeted mutation 2, En Li
MGI:1857693
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Smad2tm2Enl/Smad2tm2Enl involves: 129S4/SvJae MGI:2182385
ht2
 		Smad2tm2Enl/Smad2+ involves: 129S4/SvJae MGI:2182386


Genotype
MGI:2182385
hm1
Allelic
Composition		 Smad2tm2Enl/Smad2tm2Enl
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smad2tm2Enl mutation (0 available); any Smad2 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:48467 )
• phenotype is stated to be identical to that of Smad2tm1Enl homozygotes; however no data is presented in J:48467

embryo

growth/size/body
embryonic growth retardation ( J:48467 )




Genotype
MGI:2182386
ht2
Allelic
Composition		 Smad2tm2Enl/Smad2+
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smad2tm2Enl mutation (0 available); any Smad2 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal embryonic tissue morphology ( J:48467 )
• phenotype is stated to be identical to that of Smad2tm1Enl heterozygotes; however no data is presented in J:48467

craniofacial

growth/size/body
embryonic growth retardation ( J:48467 )

skeleton

vision/eye




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory