About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Smad2tm2Enl
targeted mutation 2, En Li
MGI:1857693
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Smad2tm2Enl/Smad2tm2Enl involves: 129S4/SvJae MGI:2182385
ht2
 		Smad2tm2Enl/Smad2+ involves: 129S4/SvJae MGI:2182386


Genotype
MGI:2182385
hm1
Allelic
Composition		 Smad2tm2Enl/Smad2tm2Enl
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smad2tm2Enl mutation (0 available); any Smad2 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality, complete penetrance ( J:48467 )
• phenotype is stated to be identical to that of Smad2tm1Enl homozygotes; however no data is presented in J:48467

embryo

growth/size/body
embryonic growth retardation ( J:48467 )




Genotype
MGI:2182386
ht2
Allelic
Composition		 Smad2tm2Enl/Smad2+
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smad2tm2Enl mutation (0 available); any Smad2 mutation (52 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
abnormal embryonic tissue morphology ( J:48467 )
• phenotype is stated to be identical to that of Smad2tm1Enl heterozygotes; however no data is presented in J:48467

craniofacial

growth/size/body
embryonic growth retardation ( J:48467 )

skeleton

vision/eye




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory