Phenotypes associated with this allele

• Allele Symbol: Mitf^mi-enu122
• Allele Name: microphthalmia enu 122
• Allele ID: MGI:1857751
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Mitf^mi-enu122/Mitf^mi-enu122	involves: 102 * C3H	MGI:3587635
ht2	Mitf^mi-enu122/Mitf^+	involves: 102 * C3H	MGI:3587636

Genotype
MGI:3587635

hm1

• Allelic Composition: Mitf^mi-enu122/Mitf^mi-enu122
• Genetic Background: involves: 102 * C3H

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Mitf^mi-enu122/Mitf^mi-enu122 mouse

vision/eye

decreased eye pigmentation ( J:46254 , J:63651 )

• severely reduced eye pigmentation (J:46254)

• pink eyes (J:63651)

microphthalmia ( J:46254 )

• some reduction in the size of the eyes

pigmentation

irregular coat pigmentation ( J:46254 )

• mostly white with diffuse, faintly pigmented patches in coat

abnormal foot pigmentation ( J:46254 )

• feet white

decreased tail pigmentation ( J:46254 )

• white

decreased eye pigmentation ( J:46254 , J:63651 )

• severely reduced eye pigmentation (J:46254)

• pink eyes (J:63651)

limbs/digits/tail

decreased tail pigmentation ( J:46254 )

• white

integument

irregular coat pigmentation ( J:46254 )

• mostly white with diffuse, faintly pigmented patches in coat

abnormal foot pigmentation ( J:46254 )

• feet white

decreased tail pigmentation ( J:46254 )

• white

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
ocular albinism with sensorineural deafness		DOID:0090100		J:46254
Tietz syndrome		DOID:0090002	OMIM:103500	J:46254
Waardenburg syndrome type 2A		DOID:0110950	OMIM:193510	J:46254

Genotype
MGI:3587636

ht2

• Allelic Composition: Mitf^mi-enu122/Mitf⁺
• Genetic Background: involves: 102 * C3H

vision/eye

abnormal retina pigmentation ( J:46254 )

• reduced retinal pigmentation

• iris and coat pigmentation normal and eye size normal

pigmentation

abnormal retina pigmentation ( J:46254 )

• reduced retinal pigmentation

• iris and coat pigmentation normal and eye size normal

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
ocular albinism with sensorineural deafness		DOID:0090100		J:46254
Tietz syndrome		DOID:0090002	OMIM:103500	J:46254
Waardenburg syndrome type 2A		DOID:0110950	OMIM:193510	J:46254