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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
t+
wild type
MGI:1857759
Summary 59 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
th7m/t+ Not Specified MGI:5465170
ht2
th7m2/t+ Not Specified MGI:5465171
ht3
tlow2H/t+ Not Specified MGI:5465167
ht4
tTu3/t+ Not Specified MGI:5284994
cx5
T24H/T+
th2/t+
involves: 101/H * C3H/HeH MGI:5471531
cx6
T34H/T+
tw32/t+
involves: 101/H * C3H/HeH * STOCK T34H * TFH MGI:3719857
cx7
T30H/T+
t6/t+
involves: 101/H * C3H/HeH * TFH MGI:3719859
cx8
T31H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH MGI:3719842
cx9
T30H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH MGI:3719846
cx10
T33H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH MGI:3719847
cx11
T36H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH MGI:3719852
cx12
T32H/T+
th51/t+
involves: 101/H * C3H/HeH * TFH MGI:3719853
cx13
T32H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH MGI:3719856
cx14
T32H/T+
t6/t+
involves: 101/H * C3H/HeH * TFH MGI:3719860
cx15
T36H/T+
t6/t+
involves: 101/H * C3H/HeH * TFH MGI:3719862
cx16
T22H/T+
tw32/t+
involves: 101/H * C3H/HeH * TFH MGI:3719863
cx17
Nme3tm1Bgh/Nme3+
tw18/t+
involves: 129S1/Sv MGI:5319399
cx18
Nme3tm1Bgh/Nme3+
th49/t+
involves: 129S1/Sv MGI:5319401
cx19
tw73 +/t+ Del(17D17Jcs40-D17Mit198)7Jcs involves: 129S4/SvJae * C3HeB/FeJ * C57BL/6J MGI:5428468
cx20
tw18/t+
Tiam2tm1Bgh/Tiam2tm1Bgh
involves: 129S/SvEv * 129S1/Sv MGI:6360722
cx21
tw18/t+
Tiam2tm1Bgh/Tiam2+
Tg(Ace-Tiam2)C11S1Bgh/0
involves: 129S/SvEv * 129S1/Sv MGI:6360725
cx22
t6/Tagaptm1Bgh involves: BALB/c * BTBR/TF * FVB/N MGI:3639742
cx23
T4J/t6 involves: BALB/cBy MGI:4830251
cx24
T29H/T+
tw32/t+
involves: BALB/c * TFH MGI:3719854
cx25
T29H/T+
t6/t+
involves: BALB/c * TFH MGI:3719858
cx26
Fgd2tm1Bgh/Fgd2+
th49/t+
involves: BTBR MGI:3700705
cx27
Itpr3tf/Itpr3+
T/T+
thr4/t+
involves: BTBR MGI:5465159
cx28
T/T+
th7m2/t+
Itpr3tf/Itpr3+
involves: BTBR MGI:5465016
cx29
t+/th20
Itpr3tf/Itpr3tf
involves: BTBR MGI:4868369
cx30
Itpr3tf/Itpr3+
th7m2/t+
involves: BTBR MGI:5465015
cx31
T/twPas1 involves: BTBR/Nev T * M. m. brevirostris MGI:4821115
cx32
Tc/th51
Tg(T)118.9Bgh/0
involves: C57BL/6 * CBA MGI:3784944
cx33
th49/t+
Tg(Ace-Tiam2)C1L2Bgh/0
involves: C57BL/6J MGI:6360724
cx34
th49/t+
Tg(Ace-Tiam2)C1L1Bgh/0
involves: C57BL/6J MGI:6360723
cx35
T5J/t6 involves: C57BL/6J MGI:4830536
cx36
T/tbtm involves: C57BL/6 * MOL-NIS MGI:4457262
cx37
T/twPas2 involves: M. m. brevirostris MGI:4821153
cx38
T/twPas3 involves: M. m. domesticus MGI:4821268
cx39
T/tw73 involves: M. m. musculus MGI:5288480
cx40
T/tbtm MOL-NIS MGI:4819839
cx41
T/T+
th7m/t+
Not Specified MGI:5465011
cx42
T t+/T+ tTu3 Not Specified MGI:5284985
cx43
T th20/T+ t+ Not Specified MGI:4868366
cx44
T/T+
th7m2/t+
Not Specified MGI:5465018
cx45
T/T+
thr1/t+
Not Specified MGI:5465026
cx46
T/T+
thr15/t+
Not Specified MGI:5465028
cx47
T/T+
thr4/t+
Not Specified MGI:5465155
cx48
T t+/T+ th45 Not Specified MGI:4868204
cx49
T/T+
tlow2H/t+
Not Specified MGI:5465165
cx50
T t+/T+ th17 Not Specified MGI:4844309
cx51
T ts6/T+ t+ Not Specified MGI:4839335
cx52
T/t6 Not Specified MGI:3663265
cx53
T/tw3 Not Specified MGI:5906043
cx54
T/tAE5 Not Specified MGI:4461426
cx55
T/t4 Not Specified MGI:4461305
cx56
T/twN27 Not Specified MGI:4460903
cx57
T/tks1 Not Specified MGI:4458399
cx58
Th/t13 Not Specified MGI:4360117
cx59
t6/t+
Tg(Ace-Nme3)H17Bgh/0
Not Specified MGI:5319402


Genotype
MGI:5465170
ht1
Allelic
Composition
th7m/t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
th7m mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• males exhibit normal transmission ratio




Genotype
MGI:5465171
ht2
Allelic
Composition
th7m2/t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
th7m2 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• male mice exhibit moderately high transmission of th7m2




Genotype
MGI:5465167
ht3
Allelic
Composition
tlow2H/t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
tlow2H mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• males give low ratio of tlow2H young




Genotype
MGI:5284994
ht4
Allelic
Composition
tTu3/t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
tTu3 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
N
• mice of this genotype have normal tails although combinations of some other t haplotypes and T produce short-tailed mice




Genotype
MGI:5471531
cx5
Allelic
Composition
T24H/T+
th2/t+
Genetic
Background
involves: 101/H * C3H/HeH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T24H mutation (0 available); any T mutation (59 available)
th2 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:3719857
cx6
Allelic
Composition
T34H/T+
tw32/t+
Genetic
Background
involves: 101/H * C3H/HeH * STOCK T34H * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T34H mutation (0 available); any T mutation (59 available)
tw32 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• fewer than expected carried the T34H allele




Genotype
MGI:3719859
cx7
Allelic
Composition
T30H/T+
t6/t+
Genetic
Background
involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T30H mutation (0 available); any T mutation (59 available)
t6 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• the transmission ratio distortion associated with t6 is increased




Genotype
MGI:3719842
cx8
Allelic
Composition
T31H/T+
tw32/t+
Genetic
Background
involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T31H mutation (0 available); any T mutation (59 available)
tw32 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system




Genotype
MGI:3719846
cx9
Allelic
Composition
T30H/T+
tw32/t+
Genetic
Background
involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T30H mutation (0 available); any T mutation (59 available)
tw32 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system




Genotype
MGI:3719847
cx10
Allelic
Composition
T33H/T+
tw32/t+
Genetic
Background
involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T33H mutation (0 available); any T mutation (59 available)
tw32 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• fewer than expected carried the T33H allele
• male fertility is low




Genotype
MGI:3719852
cx11
Allelic
Composition
T36H/T+
tw32/t+
Genetic
Background
involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T36H mutation (0 available); any T mutation (59 available)
tw32 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• viability is poor and no males survive into adulthood




Genotype
MGI:3719853
cx12
Allelic
Composition
T32H/T+
th51/t+
Genetic
Background
involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T32H mutation (0 available); any T mutation (59 available)
th51 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• fewer than expected offsprings carried the th51 allele




Genotype
MGI:3719856
cx13
Allelic
Composition
T32H/T+
tw32/t+
Genetic
Background
involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T32H mutation (0 available); any T mutation (59 available)
tw32 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• fewer than expected carried the T32H allele




Genotype
MGI:3719860
cx14
Allelic
Composition
T32H/T+
t6/t+
Genetic
Background
involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T32H mutation (0 available); any T mutation (59 available)
t6 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• the transmission ratio distortion associated with t6 is increased




Genotype
MGI:3719862
cx15
Allelic
Composition
T36H/T+
t6/t+
Genetic
Background
involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T36H mutation (0 available); any T mutation (59 available)
t6 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• the transmission ratio distortion associated with t6 is increased




Genotype
MGI:3719863
cx16
Allelic
Composition
T22H/T+
tw32/t+
Genetic
Background
involves: 101/H * C3H/HeH * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T22H mutation (0 available); any T mutation (59 available)
tw32 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system




Genotype
MGI:5319399
cx17
Allelic
Composition
Nme3tm1Bgh/Nme3+
tw18/t+
Genetic
Background
involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nme3tm1Bgh mutation (0 available); any Nme3 mutation (10 available)
tw18 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• mice exhibit increased transmission of the t-haplotype compared with wild-type mice




Genotype
MGI:5319401
cx18
Allelic
Composition
Nme3tm1Bgh/Nme3+
th49/t+
Genetic
Background
involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nme3tm1Bgh mutation (0 available); any Nme3 mutation (10 available)
th49 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• mice exhibit increased transmission of the t-haplotype compared with wild-type mice




Genotype
MGI:5428468
cx19
Allelic
Composition
tw73 +/t+ Del(17D17Jcs40-D17Mit198)7Jcs
Genetic
Background
involves: 129S4/SvJae * C3HeB/FeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(17D17Jcs40-D17Mit198)7Jcs mutation (0 available); any Del(17D17Jcs40-D17Mit198)7Jcs mutation (0 available)
tw73 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• the deletion in this genotype identifies a locus on haplotype tw73 that causes lethality at birth, tw73lab




Genotype
MGI:6360722
cx20
Allelic
Composition
tw18/t+
Tiam2tm1Bgh/Tiam2tm1Bgh
Genetic
Background
involves: 129S/SvEv * 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tiam2tm1Bgh mutation (0 available); any Tiam2 mutation (105 available)
tw18 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• whether alleles are in cis or trans, mice exhibit reduced transmission of tw18 compared with wild-type mice




Genotype
MGI:6360725
cx21
Allelic
Composition
tw18/t+
Tiam2tm1Bgh/Tiam2+
Tg(Ace-Tiam2)C11S1Bgh/0
Genetic
Background
involves: 129S/SvEv * 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ace-Tiam2)C11S1Bgh mutation (0 available)
Tiam2tm1Bgh mutation (0 available); any Tiam2 mutation (105 available)
tw18 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• mice exhibit increased transmission of tw18 compared with wild-type mice




Genotype
MGI:3639742
cx22
Allelic
Composition
t6/Tagaptm1Bgh
Genetic
Background
involves: BALB/c * BTBR/TF * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t6 mutation (0 available); any t mutation (19 available)
Tagaptm1Bgh mutation (0 available); any Tagap mutation (22 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• reduced transmission found for sperm bearing t6
• compromised sperm motility is inferred as overexpression of Tagap1 results in greater than normal t6 haplotype transmission

cellular
• reduced transmission found for sperm bearing t6
• compromised sperm motility is inferred as overexpression of Tagap1 results in greater than normal t6 haplotype transmission




Genotype
MGI:4830251
cx23
Allelic
Composition
T4J/t6
Genetic
Background
involves: BALB/cBy
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T4J mutation (1 available); any T mutation (59 available)
t6 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:3719854
cx24
Allelic
Composition
T29H/T+
tw32/t+
Genetic
Background
involves: BALB/c * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T29H mutation (0 available); any T mutation (59 available)
tw32 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• no offsprings carried the T29H allele




Genotype
MGI:3719858
cx25
Allelic
Composition
T29H/T+
t6/t+
Genetic
Background
involves: BALB/c * TFH
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T29H mutation (0 available); any T mutation (59 available)
t6 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• the transmission ratio distortion associated with t6 is increased




Genotype
MGI:3700705
cx26
Allelic
Composition
Fgd2tm1Bgh/Fgd2+
th49/t+
Genetic
Background
involves: BTBR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgd2tm1Bgh mutation (0 available); any Fgd2 mutation (34 available)
th49 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• mice transmitted the th49 allele to only 35% of their offspring compared to a transmission rate of 47% for mice without the Fgd2 mutant allele




Genotype
MGI:5465159
cx27
Allelic
Composition
Itpr3tf/Itpr3+
T/T+
thr4/t+
Genetic
Background
involves: BTBR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3tf mutation (20 available); any Itpr3 mutation (176 available)
T mutation (22 available); any T mutation (59 available)
thr4 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• high transmission ratio distortion in favour of the thr4 haplotype from males




Genotype
MGI:5465016
cx28
Allelic
Composition
T/T+
th7m2/t+
Itpr3tf/Itpr3+
Genetic
Background
involves: BTBR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3tf mutation (20 available); any Itpr3 mutation (176 available)
T mutation (22 available); any T mutation (59 available)
th7m2 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• mice exhibit normal fertility




Genotype
MGI:4868369
cx29
Allelic
Composition
t+/th20
Itpr3tf/Itpr3tf
Genetic
Background
involves: BTBR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3tf mutation (20 available); any Itpr3 mutation (176 available)
th20 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• due to a deletion associated with th20, this genotype looks like a mouse homozygous for the recessive mutation tufted




Genotype
MGI:5465015
cx30
Allelic
Composition
Itpr3tf/Itpr3+
th7m2/t+
Genetic
Background
involves: BTBR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itpr3tf mutation (20 available); any Itpr3 mutation (176 available)
th7m2 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• mice exhibit normal fertility




Genotype
MGI:4821115
cx31
Allelic
Composition
T/twPas1
Genetic
Background
involves: BTBR/Nev T * M. m. brevirostris
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
twPas1 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• when males of this genotype are mated to wild-type females the t-haplotype appears among teh offspring more frequently than expected

reproductive system




Genotype
MGI:3784944
cx32
Allelic
Composition
Tc/th51
Tg(T)118.9Bgh/0
Genetic
Background
involves: C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tc mutation (3 available); any T mutation (59 available)
Tg(T)118.9Bgh mutation (0 available)
th51 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• six of seven found to have short tails with the seventh having no tail; this is a partial rescue of the compound heterozygous phenotype in the absence of the transgene wherein sevin out of sevin have a tailless phenotype




Genotype
MGI:6360724
cx33
Allelic
Composition
th49/t+
Tg(Ace-Tiam2)C1L2Bgh/0
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ace-Tiam2)C1L2Bgh mutation (0 available)
th49 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• mice exhibit reduced transmission of th49 compared with wild-type mice




Genotype
MGI:6360723
cx34
Allelic
Composition
th49/t+
Tg(Ace-Tiam2)C1L1Bgh/0
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ace-Tiam2)C1L1Bgh mutation (0 available)
th49 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• mice exhibit reduced transmission of th49 compared with wild-type mice




Genotype
MGI:4830536
cx35
Allelic
Composition
T5J/t6
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T5J mutation (1 available); any T mutation (59 available)
t6 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:4457262
cx36
Allelic
Composition
T/tbtm
Genetic
Background
involves: C57BL/6 * MOL-NIS
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
tbtm mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
embryo
• attenuated development of the posterior part of the body
• generally distorted, duplicated or fused with the mesenchyme
• presents as a dorsal blood blister in the lumbosacral region
• E11-12 embryos show abnormalities in the medio-dorsal area
• seen in E11-12 embryos
• seen in E11-12 embryos
• at E10 a constriction occurs as the tail develops

nervous system
• generally distorted, duplicated or fused with the mesenchyme
• presents as a dorsal blood blister in the lumbosacral region
• posterior to the lumbosacral level the cord is severely distorted or duplicated and devoid of vertebrae

limbs/digits/tail
• at E10 a constriction occurs as the tail develops
• mice with this genotype lack a tail at birth and have blood listers or red scars on the dorsal skin at the middle of the lumbosacral region

skeleton
• presents as a dorsal blood blister in the lumbosacral region
• rib fusions, lack of vertebral bodies and arches
• rib fusions, lack of vertebral bodies and arches
• an abnormality of thoracic and lumbar vertebrae
• an abnormality of thoracic and lumbar vertebrae




Genotype
MGI:4821153
cx37
Allelic
Composition
T/twPas2
Genetic
Background
involves: M. m. brevirostris
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
twPas2 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail

reproductive system
• in a test cross with a wild-type female mouse the t-haplotype is seen in offspring less frequently than expected




Genotype
MGI:4821268
cx38
Allelic
Composition
T/twPas3
Genetic
Background
involves: M. m. domesticus
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
twPas3 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail

reproductive system
• when males of this genotype are mated to wild-type females the t haplotype occurs among the offspring more frequently than expected




Genotype
MGI:5288480
cx39
Allelic
Composition
T/tw73
Genetic
Background
involves: M. m. musculus
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
tw73 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• males of this genotype transmit tw73 to 88.6 per cent of offspring

limbs/digits/tail
• all mice of this genotype are tailless




Genotype
MGI:4819839
cx40
Allelic
Composition
T/tbtm
Genetic
Background
MOL-NIS
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
tbtm mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• all mice are dead by 60 days of age; the few longest-lived have hind-limb paralysis
• most die shortly after birth and have a blood blister in the lumbosacral area and hind-limb paralysis

limbs/digits/tail
• all mice of this genotype are tailless

reproductive system
N
• mice are fertile and there is no evidence of transmission ratio distortion




Genotype
MGI:5465011
cx41
Allelic
Composition
T/T+
th7m/t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
th7m mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:5284985
cx42
Allelic
Composition
T t+/T+ tTu3
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
tTu3 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
N
• the tail length is normal although a mouse inheriting a t haplotype with T is frequently tailless




Genotype
MGI:4868366
cx43
Allelic
Composition
T th20/T+ t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
th20 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:5465018
cx44
Allelic
Composition
T/T+
th7m2/t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
th7m2 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:5465026
cx45
Allelic
Composition
T/T+
thr1/t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
thr1 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:5465028
cx46
Allelic
Composition
T/T+
thr15/t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
thr15 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:5465155
cx47
Allelic
Composition
T/T+
thr4/t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
thr4 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:4868204
cx48
Allelic
Composition
T t+/T+ th45
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
th45 mutation (1 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:5465165
cx49
Allelic
Composition
T/T+
tlow2H/t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
tlow2H mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
N
• no effect on tail length




Genotype
MGI:4844309
cx50
Allelic
Composition
T t+/T+ th17
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
th17 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
normal phenotype
• mice with this genotype have short tails; they are not tailless as are mice heterozygous for brachyury and carrying any of the majority of other t haplotypes
• there is no transmission ratio distortion as might be expected from males of this genotype




Genotype
MGI:4839335
cx51
Allelic
Composition
T ts6/T+ t+
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
ts6 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• 85% of offspring produced from 3 matings of Tts6 males to wild-type females are short-tailed; 15% are normal-tailed




Genotype
MGI:3663265
cx52
Allelic
Composition
T/t6
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
t6 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 69% of the normal size

embryo
• the notochord is increased in bulk not only in the distal growth zone (as in T heterozygotes) but in the whole tail, in the cloacal region and even more anteriorly in the lumbar region and has large lumina
• the notochord is present throughout the length of the tail, however it becomes incorporated into the neural tube throughout the tail and often the cloacal region
• the size of the ventral ectodermal ridge of the tail (VER) is reduced to 69% of the normal size




Genotype
MGI:5906043
cx53
Allelic
Composition
T/tw3
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
tw3 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:4461426
cx54
Allelic
Composition
T/tAE5
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
tAE5 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:4461305
cx55
Allelic
Composition
T/t4
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
t4 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail

reproductive system
• T-bearing gametes are in excess although not uniformly the case from male to male




Genotype
MGI:4460903
cx56
Allelic
Composition
T/twN27
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
twN27 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• indicative of the presence of a t haplotype




Genotype
MGI:4458399
cx57
Allelic
Composition
T/tks1
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
T mutation (22 available); any T mutation (59 available)
tks1 mutation (0 available); any t mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail

reproductive system
• only 37% of sperm from males of this genotype carry the tks1 haplotype




Genotype
MGI:4360117
cx58
Allelic
Composition
Th/t13
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t13 mutation (0 available); any t mutation (19 available)
Th mutation (0 available); any T mutation (59 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail




Genotype
MGI:5319402
cx59
Allelic
Composition
t6/t+
Tg(Ace-Nme3)H17Bgh/0
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
t6 mutation (0 available); any t mutation (19 available)
Tg(Ace-Nme3)H17Bgh mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
• the transmission ratio distortion associated with t6 is decreased





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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory