All Phenotypes Mesp1<tm1Ysa> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Mesp1^tm1Ysa
targeted mutation 1, Yumiko Saga
MGI:1857785

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Mesp1^tm1Ysa/Mesp1^tm3Ysa	involves: C57BL/6 * CBA * ICR	MGI:3702403

Allelic Composition	Mesp1^tm1Ysa/Mesp1^tm3Ysa
Genetic Background	involves: C57BL/6 * CBA * ICR

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mesp1^tm1Ysa mutation (1 available); any Mesp1 mutation (18 available)
Mesp1^tm3Ysa mutation (1 available); any Mesp1 mutation (18 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal mesoderm development ( J:55840 )

• mesodermal cells fail to migrate out of the primitive streak

abnormal primitive streak morphology ( J:55840 )

• exhibit an abnormal accumulation of beta-gal-positive mesodermal cells in the primitive streak as these cells do not actively migrate out from the primitive streak

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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