About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Oas1bFlv-r
flavivirus resistance
MGI:1857800
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Oas1bFlv-r/Oas1bFlv-r C3.PRI-Oas1bFlv-r MGI:5285417
hm2
 		Oas1bFlv-r/Oas1bFlv-r multiple strains MGI:2429410


Genotype
MGI:5285417
hm1
Allelic
Composition		 Oas1bFlv-r/Oas1bFlv-r
Genetic
Background		 C3.PRI-Oas1bFlv-r
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oas1bFlv-r mutation (2 available); any Oas1b mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to Flaviviridae infection ( J:175365 )
• mice infected with 17D yellow fever virus do not develop disease symptoms unlike C3H/He mice




Genotype
MGI:2429410
hm2
Allelic
Composition		 Oas1bFlv-r/Oas1bFlv-r
Genetic
Background		 multiple strains
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Oas1bFlv-r mutation (2 available); any Oas1b mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to Flaviviridae infection ( J:15009 )
• viral replication was inhibited in mice from resistant strains upon innoculation with the following viruses: Yellow Fever, Dengue Fever, West Nile Fever, Japanese Encephalitis, St. Louis Encephalitis, Russian Spring Summer Encephalities




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory